现代食品科技2017，Vol.33Issue(7)：50-55,6.DOI:10.13982/j.mfst.1673-9078.2017.7.008
麦麸提取物对晚期糖基化终产物的抑制研究
Stunhibitory Effect of Wheat Bran Extract on the Advanced Glycation End Products
摘要
Abstract
Cereal foods are important for human health and for the control and prevention of cancer,heart disease,and diabetes,while advanced glycation end products (AGEs) can induce the occurrence of diabetes and other complications.Therefore,feruloyl oligosaccharides and wheat bran hydrolysate were selected as the inhibitors in this experiment to study their inhibitory effects on the formation of AGEs in bovine serum albumin-glucose system.Ferulic acid,xylooligosaccharides,and insoluble dietary fiber were used as controls,and the fluorescent and non-fluorescent products (Nε-carboxymethyllysine and CML) of AGEs were used to evaluate the effects of the inhibitors.The results indicated that the contents of total polyphenol and total flavonoids in feruloyl oligosaccharides were 5.36 and 2.67 times as much as those in wheat bran hydrolysate,respectively.The inhibition rates of feruloyl oligosaccharides and wheat bran hydrolysates on the fluorescent products were 14.49％ and 5.75％,respectively,and their inhibition rates on the non-fluorescent product CML were 18.16％ and 16.59％,respectively.The different inhibition rates might be related to the varying levels of total polyphenols and flavonoids.Ferulic acid,xylooligosaccharides,and insoluble dietary fiber groups showed no inhibitory effect on the production of fluorescent and non-fluorescent products.As evident from the amounts of reducing sugar and lysine in the simulation system before and after the reaction,feruloyl oligosaccharides and wheat bran hydrolysate may inhibit the glycosylation reaction by reducing the content of available lysine in the reactive proteins.关键词
晚期糖基化终产物/阿魏酰低聚糖/麦麸酶解物/抑制Key words
advanced glycation end products/feruloyl oligosaccharides/wheat bran hydrolysate/inhibition引用本文复制引用
刘慧琳,陈晓默,倪天鸿,王静..麦麸提取物对晚期糖基化终产物的抑制研究[J].现代食品科技,2017,33(7):50-55,6.基金项目
国家自然科学基金项目(31571940) （31571940）
