食品科学2017，Vol.38Issue(13)：213-218,6.DOI:10.7506/spkx1002-6630-201713035
刺玫籽油及原花青素降血脂作用
Hypolipidemic Activity of Seed Oil and Procyanidins of Rosa davurica Pall.
摘要
Abstract
The hypolipidemic activity of the seed oil and procyanidins of Rosa davurica Pall.was investigated by animal tests.Kunming male mice fed a high fat diet were used as a hyperlipidemic animal model.After oral administration for 5 weeks,serum and liver homogenate were collected for the measurement of parameters of interest.Compared with the hyperlipidemic model group,both drugs had no significant effect on body weight and visceral organ indexes in mice.The proanthocyanidins at middle (100 mg/kg) and high doses (200 mg/kg) could significantly reduce serum LDL-C,TC and TG (P ＜ 0.05),significantly improve liver superoxide dismutase (SOD),catalase (CAT) and glutathione peroxidase (GSH-Px) levels (P ＜ 0.05),and significantly decrease liver MDA level.The oil at low dose (80 mg/kg) could evidently reduce serum TG levels in hyperlipidemic mice (P ＜ 0.05) and significantly increase in liver CAT activity (P ＜ 0.05).Therefore,the seed oil at low dose and the procyanidins at middle and high doses play a role in reducing blood lipids in hyperlipidemic mice.关键词
刺玫籽油/原花青素/降血脂Key words
Rosa davurica Pall.seed oil/procyanidins/lipid-lowering activity分类
轻工纺织引用本文复制引用
胡济美,李倬林,岳玉兰,容晨曦,黄威,薛培宇,李铁柱,张杰..刺玫籽油及原花青素降血脂作用[J].食品科学,2017,38(13):213-218,6.基金项目
吉林省科学技术厅重点科技攻关项目(20140204051YY) （20140204051YY）
吉林省科技厅重大科技攻关专项(20140203014NY) （20140203014NY）
