中国食物与营养2017，Vol.23Issue(6)：12-17,6.
转DBN9978基因抗虫抗除草剂玉米对大鼠的亚慢性毒性研究
Subchronic Toxicity Test of Genetic Modified Corn with DBN9978 Gene in Rats
摘要
Abstract
[Objective] The subchronic toxicity of feed with DBN9978 genetic modified corn was tested in rats.[Method] A total of 140 SD rats were randomly divided into 7 groups with 20 rats each group including three transgenic corn groups with different doses (73.3％,36.65％,18.33％),three containing non-transgenic corn (72.7％,35.35％,18.18),1 routine Basal diet control group.Animals 2/cage feeding,free to eat drinking water,continuous observation of 90 days.Observation of body weight,food intake,the blood routine test,blood biochemistry test (at the 45 th day and the 90 th day of the experiment),organ weight and organ pathological examination (at the end of the 90 th day) were conducted.[Result] The weight of the animals in each dose group showed an increasing trend.The weight and weight gain,weekly food intake,total food utilization rate and blood and blood biochemical indexes of the transgenic corn groups,containing non-transgenic corn group and the feeding control group,The main organ coefficient and histopathological examination were found no significant changes in biological significance.[Conclusion] There were no enough evidences to confirm GM corn with DBN9978 genes has subchronic toxic effects on rat.关键词
转基因玉米/DBN9978基因/亚慢性毒性Key words
genetically modified corn/DBN9978 gene/subchronic toxicity引用本文复制引用
王睿,胡贻椿,李敏,吴景欢,杨晓光,毛德倩..转DBN9978基因抗虫抗除草剂玉米对大鼠的亚慢性毒性研究[J].中国食物与营养,2017,23(6):12-17,6.基金项目
国家科技重大专项——转基因生物新品种培育“抗虫抗除草剂转基因玉米食品安全评价研究”. （）
