食品工业科技2017，Vol.38Issue(12)：258-263,6.DOI:10.13386/j.issn1002-0306.2017.12.047
薏苡仁油β-环糊精包合物的制备及其表征
Preparation and characterization of Adlay seed oil and β-cyclodextrin inclusion complexes
摘要
Abstract
To prepare the β-cyclodextrin inclusion of Adlay seed oil with a saturated aqueous solution.The optimum by Box-Behnken response surface design were as follows-the ratio ofβ-CD to Adlay seed oil 9∶1 (g/g),stirring temperature 45 ℃,inclusion time 6 h.The inclusion was characterized hy SEM,DSC,FT1R and XRD.Entrapment efficiency of the inclusion determined by HPLC was 63％.In the acute toxicity test,the mice which were fed with the highest concentration(63 mg/mL) and maximum dosage(0.04 mL/g),no death was found in the experimental mice after 14 days.No organ abnormalities were found and no organ pathology in sliced observation.The prelpared inclusion complexes were safety for oral administration to be better for further study of efficacy.关键词
薏苡仁油/β-CD包合物/Box-Behnken响应面设计/高效液相/急性毒性实验Key words
Adlay seed oil/β3-cyclodextrin inclusion/Box-Behnken response surface design/HPLC/acute toxicity test分类
轻工纺织引用本文复制引用
徐蓉蓉,高垚垚,周云龙,胡荣..薏苡仁油β-环糊精包合物的制备及其表征[J].食品工业科技,2017,38(12):258-263,6.基金项目
扬州大学(大学生)科技创新基金项目(x20160794). （大学生）
