食品科学2017,Vol.38Issue(15):265-270,6.DOI:10.7506/spkx1002-6630-201715042
不同诱导物对内皮细胞氧化损伤作用的研究进展
Progress in Research on Effects of Different Inducers on Oxidative Damage in Endothelial Cells
摘要
Abstract
Nowadays,the incidence of hypertension,atherosclerosis and other cardiovascular and cerebrovascular diseases,which threaten human health,increases year by year.Previous studies showed that oxidative damage in endothelial cells was usually a common response at the early stage of these diseases.Moreover,some therapeutic strategies such as physical therapy and cardiac surgery may leave some problems affecting endothelial function.In this context,the mechanism of oxidative damage in endothelial cells is of growing interest to researchers,and many efforts have been made to seek the most suitable effectors like active components derived from foods to inhibit oxidative damage in endothelial cells,thereby preventing or reducing the occurrence of related diseases.The mechanisms of action of several common inducers such as hydrogen peroxide,oxidized low-density lipoprotein,high glucose concentration and radiation in causing oxidative damage in endothelial cells are described in this review,which will provide valuable information to select a suitable inducer for induction of oxidative damage in endothelial cells and therefore to facilitate the selection of effectors and the study of the underlying mechanism.关键词
内皮细胞/氧化损伤/诱导物Key words
endothelial cells/oxidative damage/inducer分类
轻工纺织引用本文复制引用
梁盈,李佳佳,黄萍,马酉初,刘一超,林亲录..不同诱导物对内皮细胞氧化损伤作用的研究进展[J].食品科学,2017,38(15):265-270,6.基金项目
国家自然科学基金青年科学基金项目(31201348) (31201348)
国家自然科学基金面上项目(31571874)湖南省自然科学基金面上项目(2017JJ2410) (31571874)
湖湘青年科技创新人才项目(2016RS3033) (2016RS3033)
粮油深加工与品质控制2011湖南省协同创新项目 ()
中南林业科技大学研究生教材建设项目(2015JC03) (2015JC03)