现代食品科技2017，Vol.33Issue(8)：12-17,40,7.DOI:10.13982/j.mfst.1673-9078.2017.8.003
桑叶-苦瓜混合粉对糖尿病小鼠血脂的影响
Effects of Mulberry Leaf and Balsam Pear Mixed Powder on Blood Lipid Metabolism in Diabetic Mice
摘要
Abstract
This study aimed to investigate the effect of mulberry leaf and balsam spear mixed powder on blood lipid metabolism in diabetic mice,and provide a reference for the development and utilization of healthy food with hypoglycemic and antidiabetic activities.A mouse model of diabetes mellitus was established,and the animals were fed a basal or high-fat diet along with different doses of mulberry leaf and balsam spear mixed powder.Blood samples were collected 30 d later to measure changes in the serum biochemical indices related to lipid metabolism in the mice.The results showed that when the mice were fed 0.5 ml of 0.20 g/mL mulberry leaf and balsam spear mixed powder solution,the levels of total cholesterol (TC),tdglyceride (TG),and low-density lipoprotein cholesterol (LDL-C) in the diabetic mice fed with basal or high-fat diets were significantly lower than those in the control group (p＜0.05).In addition,the high-density lipoprotein cholesterol (HDL-C) levels were significantly higher than that of the control group.For female and male mice fed the basal diet,LDL-C values decreased by 57.14％ and 57.41％,respectively;HDL-C values increased by 96.97％ and 95.45％,respectively;TC values decreased by 14.58％ and 18.45％,respectively;and TG values decreased by 20,57％ and 21.98％,respectively.All values of blood lipid indicators tended to be close to normal values.Therefore,the intake of mulberry leaves-bitter gourd mixed powder with diet control can have a beneficial hypolipidemic effect in diabetic mice.关键词
桑叶-苦瓜混合粉/糖尿病/血脂Key words
mulberry leaf and balsam pear mixed powder/diabetes/blood lipid引用本文复制引用
杨敏,丁晓雯,秦樱瑞,黄先智..桑叶-苦瓜混合粉对糖尿病小鼠血脂的影响[J].现代食品科技,2017,33(8):12-17,40,7.基金项目
国家现代农业(桑蚕)产业技术体系建设专项(CARS-22-ZJ0503) （桑蚕）
