现代食品科技2017，Vol.33Issue(8)：24-29,6.DOI:10.13982/j.mfst.1673-9078.2017.8.005
核桃仁种皮多酚对免疫抑制小鼠的调节作用
Effect of Polyphenols from Walnut Kernel Pellicle on Immunosuppressed Mice
闫国培 1刘会平 1孙娜新 1闫哲贤 1史玉明 1姜洋 1袁晋芳1
作者信息
- 1. 食品营养与安全教育部重点实验室,天津科技大学食品工程与生物技术学院,天津300457
- 折叠
摘要
Abstract
An immunosuppressed mouse model,established through intraperitoneal injection of specific pathogen-free mice with cyclophosphamide (CTX),was used to study the immunomodulatory effect of walnut kemel pellicle polyphenols (WKPs).The mice were randomly divided into five groups:normal group,model group,and low-dose (50 mg/kg),medium-dose (100 mg/kg),and high-dose (200mg/kg) WKP groups.The effect of different doses of WKPs on the thymus and spleen indexes,phagocytic index,blood-related indicators,immunoglobulin (Ig) G,IgA,and IgM levels,and lactic dehydrogenase (LDH) and acid phosphatase (ACP) activities were investigated.Consequently,in the immunosuppressed mice,the WKPs had a definite effect on improving and enhancing immune functions,by improving the organ index,increasing the carbon clearance index,increasing the rate of lymphocyte proliferation,maintaining the balance of blood cell distribution to some extent,increasing the immunoglobulin content,enhancing the activities of LDH and ACP,and maintaining the stability of physiological indexes.关键词
核桃仁种皮/多酚/免疫功能Key words
walnut kernel pellicle/polyphenols/immunological function引用本文复制引用
闫国培,刘会平,孙娜新,闫哲贤,史玉明,姜洋,袁晋芳..核桃仁种皮多酚对免疫抑制小鼠的调节作用[J].现代食品科技,2017,33(8):24-29,6.
