食品工业科技2017，Vol.38Issue(14)：244-247,4.DOI:10.13386/j.issn1002-0306.2017.14.047
三氯蔗糖-6-乙酸酯醇解制三氯蔗糖及结晶工艺优化
Study on the conversion process of sucralose-6-acetate to sucralose in methanol and recrystallized process improvement
摘要
Abstract
Sucralose was obtained from sucralose-6-acetate under the conditions of alkaline content of sucralose as index,investigated the effects of reaction temperature,pH and reaction time on deacetylation by mixed-level uniform design.Data processing software (DPS) was used to obtain the result that the average yield of sucralose was 79.49％ at the reaction temperature 35.0 ℃,adjusted to pH =10.0 and reaction time 2.3 h.The absolute deviation relative to model-calculated theoretical value was 1.26％.These results showed the feasibility for design the conversion process of sucralose-6-acetate and obtained the optimal conditions of the alcoholysis by DPS.In the recrystallization purification process,the ethyl acetate and butyl acetate were used as extracting agent,the organic phase was washed several times by distilled water and then the water phase was collected.Then the TGS product was obtained by the proceture of actived carbon decoloration,filtration,ultrasonic,cooling,recrystallization,drying and other processes.Analyzed by IR and HPLC,the highest purity of TGS was up to 99.23％ and the water content was less than 1.0％.It had provided a feasible method for sucralose industrialized production and crystallization purification technology.关键词
三氯蔗糖-6-乙酸酯/三氯蔗糖/醇解/结晶提纯Key words
sucralose-6-acetate/sucralose/alcoholysis/crystallization purification分类
轻工纺织引用本文复制引用
潘浩然,粟晖,姚志湘,刘柳,刘春水..三氯蔗糖-6-乙酸酯醇解制三氯蔗糖及结晶工艺优化[J].食品工业科技,2017,38(14):244-247,4.基金项目
广西科技大学研究生创新计划项目(GKYC201608) （GKYC201608）
广西糖资源绿色加工重点实验室、广西高校糖资源加工重点实验室开放基金(2015TZYKF08) （2015TZYKF08）
