食品工业科技2017，Vol.38Issue(19)：293-297,5.DOI:10.13386/j.issn1002-0306.2017.19.054
蓓蕾蓝靛果花色苷对乙醇诱导小鼠氧化损伤的保护作用
Protection of Lonicera caerulea ‘ Beilei’ anthocyanins on oxidative injury of mice induced by ethanol
摘要
Abstract
To explore the protection of Lonicera caerulea ‘Beilei’ anthocyanins on ethanol induced oxidative injury in mice.According to the weight,mice were randomly divided into 6 groups,the control group,model group,Vc control group (20 mg/kg BW),anthocyanins low dose group (50 mg/kg BW),anthocyanin medium dose group (100 mg/kg BW)and anthocyanin high dose group(200 mg/kg BW).The volume of oral garage was 0.2 mL/10 g per day,and the control group and model group were filled with normal saline.After 30 days,the oxidative damage model was induced by oral gavage with ethanol except the control group.The content of malondialdehyde (MDA),protein carbonyl (PC),superoxide dismutase (SOD),glutathione peroxidase (GSH-PX) and glutathione (GSH) in blood and tissues were detected.Results showed that Lonicera caerulea ‘Beilei’ anthocyanins could significantly reduce the content of MDA and PC in mice (p ＜ 0.01),and it could significantly(p ＜0.01)improve the activity of SOD and GSH-PX in vivo and raise the content of GSH.Lonicera caerulea ‘ Beilei’ anthocyanins have protective effect in preventing oxidative damage in mice.关键词
蓓蕾蓝靛果/花色苷/乙醇/氧化损伤Key words
Lonicera caerulea ‘ Beilei’/anthocyanin/ethanol/oxidative damage分类
轻工纺织引用本文复制引用
周丽萍,张悦,王化,李梦莎,何丹娆,杜凤国..蓓蕾蓝靛果花色苷对乙醇诱导小鼠氧化损伤的保护作用[J].食品工业科技,2017,38(19):293-297,5.基金项目
“十三五”国家重点研发计划(2016YFC500300) （2016YFC500300）
黑龙江省科学院院基金项目(2014) （2014）
黑龙江省科学院对外合作基金项目(2016). （2016）
