食品工业科技2017，Vol.38Issue(19)：346-351,6.DOI:10.13386/j.issn1002-0306.2017.19.064
秀丽隐杆线虫在降脂类生物活性物质功能评价中的应用研究进展
Research progress on application of Caenorhabditis elegans in function evaluation of lipid-lowering bioactive substances
摘要
Abstract
Excessive deposition of fat can cause chronic diseases such as hyperlipidemia,cardiovascular and cerebrovascular diseases and diabetes.Caenorhabditis elegans has the advantages of simple structure,transparent body,convenient observation,short development cycle,easy cultivation and the highly conserved signaling pathway,which make possible research on fat regulation of Caenorbabditis elegans.This paper introduces the advantage of Caenorhabditis elegans as a model organism for studying fat metabolism,reviews the recent studies on the bioactive substances with lipid-lowering function,and summarizes the lipid metabolism in Caenorhabditis elegans and application of Caenorhabditis elegans in lipid metabolism,which provide an important basis for the study of lipid-lowering drugs and the study of metabolic disorders such as obesity.关键词
秀丽隐杆线虫/降血脂/生物活性物质/应用研究Key words
Caenorhabditis elegans/lipid-lowering/bioactive substances/application research分类
轻工纺织引用本文复制引用
冯亚芳,米生权..秀丽隐杆线虫在降脂类生物活性物质功能评价中的应用研究进展[J].食品工业科技,2017,38(19):346-351,6.基金项目
北京市教委研究项目资助(SQKM201311417014). （SQKM201311417014）
