中国食物与营养2017，Vol.23Issue(7)：76-79,83,5.
晚期糖基化终末产物与糖尿病血管并发症
Advanced Glycation End Products and Diabetic Vascular Complications
摘要
Abstract
Advanced glycatiou end products (AGEs) are a heterogenous group of molecules generated through non-enzymatic glycation and oxidation of proteins,lipids and nucleic acids.The direct modification of proteins,lipids.nucleic acids of AGEs or the interaction of AGEs with their receptor elicit oxidative stress generation and as a result evokes proliferative,inflammatory,thrombotic and fibrotic reactions in a variety of cells,which can accelerate the aging of the human boty or lead to a variety of chronic diseases.Here is to nake a review of the moleccular mechanism of AGEs as well as the role of AGEs in diabetic vascular complications.关键词
晚期糖基化终末产物/糖尿病血管并发症/研究进展Key words
advanced glycation end product/diabetic vascular complication/research progress引用本文复制引用
张黎,任锦丽,张召锋..晚期糖基化终末产物与糖尿病血管并发症[J].中国食物与营养,2017,23(7):76-79,83,5.基金项目
国家自然科学基金项目(项目编号:81472970). （项目编号:81472970）
