中国食品添加剂Issue(12)：57-61,5.
桑黄子实体与菌丝多糖抗肿瘤活性研究
Anti-tumor activity of polysaccharides from Phellinus igniarius fruiting body and mycelium
摘要
Abstract
Polysaccharides are the main bioactive components of Phellinus igniarius,it exists in Phellinus igniarius fruiting body,fermentation broth and mycelium of Phellinus igniarius.In this experiment,the extraction,molecular structure and anti-tumor activity of polysaccharides from fruiting body and two growth phase of mycelium were studied.The composition of polysaccharides monosaccharide of fruiting body are:galactose,glucose,xylose and mannose;polysaccharides monosaccharide composition of phellinus igniarius mycelial are:galactose,glucose and mannose.Two polysaccharides had different structure.The anti-tumor experiments showed that the IC5o values of inhibition rate of fruiting body polysaccharide on hepatoma carcinoma cell (HepG2),lung cancer cell (A549),hepatoma carcinoma cell (Hela) were 0.34 mg/mL,0.65 mg/mL,0.95mg/mL.The anti-tumor effect of Phellinus igniarius polysaccharide was significantly higher than that of mycelium polysaccharide;different growth period of polysaccharides mycelium had different anti-tumor activity,polysaccharides of mycelium within short growing period exhibited stronger anti-tumor activity.The experimental results provided an important theoretical basis for industrial of Phellinus igniarius in the future.关键词
桑黄/多糖/菌丝/抗肿瘤/子实体Key words
phellinus igniarius/polysaccharides/mycelium/anti-tumor/fruiting body分类
生物科学引用本文复制引用
应瑞峰,吴彩娥,黄梅桂,王耀松..桑黄子实体与菌丝多糖抗肿瘤活性研究[J].中国食品添加剂,2017,(12):57-61,5.基金项目
国家自然青年科学基金资助项目(31600153) （31600153）
南京林业大学引进高层次人才和高层次留学回国人员科研基金(GXL2013026) （GXL2013026）
大学生实践创新训练计划项目. （）
