食品工业科技2017,Vol.38Issue(21):21-25,5.DOI:10.13386/j.issn1002-0306.2017.21.005
姜黄素超分子包合物的结构鉴定及其抗氧化活性
Structural identification of curcumin/β-cyclodextrin polymer inclusion complex and its antioxidant activity
摘要
Abstract
In this study,curcumin/β-cyclodextrin polymer inclusion complex were prepared by β-cyclodextrin polymer materials and its antioxidant activity was also studied.The content of curcumin in inclusion complex was detected by HPLC method and the structure of inclusion complex was identified by differential scanning calorimetry(DSC),X-ray diffractometry (XRD) and Fourier transform infrared spectroscopy(FT-IR).Moreover,the spectrophotometric method was used to investigate the ability of inclusion complex to scavenge 2,2-azinobis-3-ethylbenzothiazoline-6-sulfonic acid(ABTS) and 1,1-diphenyl -2-picrylhydrazyl(DPPH) radicals.The experimental results showed that the yield and the encapsulation efficiency of inclusion complex was 63.5% and 34.5%,respectively.The formation of inclusion complex was proved by DSC,FT-IR,and XRD.Antioxidant activity assay analysis showed that inclusion complex exhibited strong scavenging effects on ABTS and DPPH free radicals in a dose-and time-dependent manner.The results demonstrated that inclusion complex with certain antioxidant activity could be obtained using the method reported in this paper,which provided the new technology method and theory reference data for the formulation improvement and application of curcumin.关键词
姜黄素/β-环糊精聚合物/包合物制备/抗氧化活性Key words
curcumin/β-cyclodextrin polymer/inclusion complex preparation/anti-oxidant activity分类
轻工纺织引用本文复制引用
陈建平,彭莞仪,秦小明,谌素华,钟赛意,刘颖..姜黄素超分子包合物的结构鉴定及其抗氧化活性[J].食品工业科技,2017,38(21):21-25,5.基金项目
国家自然科学基金青年科学基金项目(21602034) (21602034)
广东省自然科学基金博士启动项目(2016A30310332) (2016A30310332)
广东省天然产物绿色加工与产品安全重点实验室开放基金(201617) (201617)
广东海洋大学科研启动项目(R17034). (R17034)