食品工业科技2017，Vol.38Issue(22)：1-4,10,5.DOI:10.13386/j.issn1002-0306.2017.22.001
胭脂萝卜天竺葵素抑制人胃癌细胞迁移与侵袭
Pelargonium from carmine radish inhibits migration and invasion of human gastric cancer
摘要
Abstract
The mechanisms of carmine radish pelargonium inhabited gastric cancer cells(MKN45)migration and invasion was investigated in the study.After different concentrations of pelargonium treatment,MTT assay,flow cytometry(FCM),cell wound healing and TranswellTM assay were used to detectthe cell proliferation,cell cycle,cell migration and invasion ability.Protein expression of E-cadherin and N-cadherin were measured with western blot.The results showed 6 μg/mL pelargonium inhibited MKN45 cell proliferation,migration and invasion remarkable,induced cell S phase arrest.E-cadherin upregulation and N-cadherin downregulation might be the major mechanisms of pelargonium inhibited cell migration and invasion.关键词
天竺葵素/胭脂萝卜/胃癌/迁移和侵袭Key words
pelargonium/carmine radish/gastric cancer/migration and invasion分类
轻工纺织引用本文复制引用
梁姗,蒋子川,冯均,龚郭超..胭脂萝卜天竺葵素抑制人胃癌细胞迁移与侵袭[J].食品工业科技,2017,38(22):1-4,10,5.基金项目
重庆市教委科研基金(KJ1601207) （KJ1601207）
长江师范学院校级科研项目(2015KYQD01). （2015KYQD01）
