食品工业科技2017，Vol.38Issue(22)：296-299,305,5.DOI:10.13386/j.issn1002-0306.2017.22.057
葡萄酒泡洋葱降脂降糖作用的研究
Study on the hypoglycemic and hypolipidemic effects of wine combined with onion
摘要
Abstract
Objective:Effect of wine combined with onion on blood glucose and blood lipid in diabetic mellitus mice was studied.Method:The diabetic mice model was built by feeding high-fat and high-carbohydrate diet and then injection of streptozotocin (STZ).According to body mass and glucose level,the mice were randomly divided into six groups:control group,model group,high,middle and low dose of wine combined with onion group,and positive control (metformin hydrochloride) group.The mice were perfused once per day for 30 days.Pancreas,liver,fasting blood glucose,blood lipid,insulin levels and the change of oxidative stress were detected.Result:Compared with the DM group,both high dose and middle dose wine combined with onion groups were filled with insulin granules,fatty degeneration of hepatocytes.Pancreas,liver were protected,and then had significant influences on the type 2-diabetic model mice,including reduced blood glucose,increased INS level,and decreased TG and TC levels (p ＜ 0.05).Serum SOD was increased,and MDA was decreased (p ＜ 0.01).Conclusion:Studies showed that high and middle dose of wine combined with onion can reduce blood glucose,improve lipid disorders and antioxidation function in DM mice.关键词
葡萄酒泡洋葱/2-型糖尿病小鼠/降血糖/降血脂Key words
wine combined with onion/diabetic mellitus mice/hypoglycemic/hypolipidemic分类
轻工纺织引用本文复制引用
张飒乐,李晓明,牛睿,杨旸,谢欣恬,方欢乐..葡萄酒泡洋葱降脂降糖作用的研究[J].食品工业科技,2017,38(22):296-299,305,5.基金项目
陕西省教育厅项目(16JK2137) （16JK2137）
西安培华学院校级重点课题(PHKT1601). （PHKT1601）
