食品工业科技2018，Vol.39Issue(2)：40-43,50,5.DOI:10.13386/j.issn1002-0306.2018.02.008
富硒青钱柳多糖对α-葡萄糖苷酶及HepG2细胞葡萄糖消耗的影响
Effects of selenium polysaccharide from Cyclocarya paliurus (Batal) Ijinskaja on α-glucosidase and glucose consumption in HepG2 cells
摘要
Abstract
The α-glucosidase and HepG2 cells were used to study the hypoglycemic activity of selenium polysaceharide from Cyclocarya paliurus(Batal)Ijinskaja(Se-CPP) in vitro.The hypoglycemic activity of Se-CPP was compared with Cyclocarya paliurus(Batal) Ijinskaja polysaccharide (CPP),CPP + selenium yeast and CPP + sodium selenite.The results showed that appropriate dose of Se-CPP could effectively inhibite the activity of o-glucosidase in a dose dependent and its 50％ inhibitory concentration was 0.054 mg/mL,which was lower than acarbose,CPP,CPP + selenium yeast and CPP + sodium selenite.Furthermore,appropriate dose of Se-CPP could improve the glucose consumption of insulin resistance HepG2 cells and the effect was better than that of CPP,CPP + selenium yeast and CPP + sodium selenite(p ＜ 0.05).关键词
富硒青钱柳多糖/α-葡萄糖苷酶/降血糖/胰岛素抵抗/HepG2细胞Key words
selenium polysaccharide from Cyclocarya paliurus (Batal) Ijinskaja/α-glucosidase/hypoglycemia/insulin resistance/HepG2 cells分类
轻工纺织引用本文复制引用
张浩,李东山,谭开祥,向极钎,刘卫..富硒青钱柳多糖对α-葡萄糖苷酶及HepG2细胞葡萄糖消耗的影响[J].食品工业科技,2018,39(2):40-43,50,5.基金项目
湖北省科技支撑计划项目(2013BEC048). （2013BEC048）
