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儿茶素EGCG抗肿瘤及其作用机制研究进展

杜晓琳 黄煌 李倩 吴正奇 陈小强 糜志远

食品工业科技2017,Vol.38Issue(24):308-314,7.
食品工业科技2017,Vol.38Issue(24):308-314,7.DOI:10.13386/j.issn1002-0306.2017.24.060

儿茶素EGCG抗肿瘤及其作用机制研究进展

Advances in anti-tumor effect of catechins EGCG and its mechanism

杜晓琳 1黄煌 1李倩 1吴正奇 1陈小强 1糜志远1

作者信息

  • 1. 湖北工业大学生物工程与食品学院,湖北武汉430068
  • 折叠

摘要

Abstract

Epigallocatechin gallate(EGCG),the highest content of tea polyphenols,has been shown to have significant anti-tumor effects,but its mechanism is complex.Combined with the latest researches,this paper reviewed that the EGCG prevented the occurrence of tumors through the anti-oxidation,anti-inflammatory and other ways;the EGCG may also exhibit anti-tumors effect by inhibiting tumor suppressor gene methylation,regulation of tumor-associated protein expression,inhibition of the tumor cell growth and disturbing the tumor cell signal transduction;the mechanism of synergistic effect between EGCG and other factors on the anti-tumor effect was summarized as well,in order to provide a theoretical basis for the further study on anti -tumor effect of EGCG.

关键词

EGCG/肿瘤/作用机制

Key words

EGCG/tumor/mechanism of action

分类

轻工纺织

引用本文复制引用

杜晓琳,黄煌,李倩,吴正奇,陈小强,糜志远..儿茶素EGCG抗肿瘤及其作用机制研究进展[J].食品工业科技,2017,38(24):308-314,7.

基金项目

“楚天学者”计划 ()

博士启动项目(BSQDI3007). (BSQDI3007)

食品工业科技

OA北大核心CSCDCSTPCD

1002-0306

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