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食品中羧甲基赖氨酸的形成机理和抑制途径研究进展

韩文凤 谭兴和 林晓丽 邱泼 孟宏昌 贾娟

现代食品科技2018,Vol.34Issue(1):245-251,7.
现代食品科技2018,Vol.34Issue(1):245-251,7.DOI:10.13982/j.mfst.1673-9078.2018.1.038

食品中羧甲基赖氨酸的形成机理和抑制途径研究进展

Research Progress on Formation Mechanism and Inhibition Pathway of Nε-(1-Carboxyethyl)-L-Lysine in Food

韩文凤 1谭兴和 2林晓丽 1邱泼 3孟宏昌 2贾娟4

作者信息

  • 1. 湖南农业大学食品科技学院,湖南长沙410128
  • 2. 漯河职业技术学院食品工程系,河南漯河462000
  • 3. 食品科学与生物技术湖南省重点实验室,湖南长沙410128
  • 4. 浙江麦吉士食品有限公司,浙江杭州310000
  • 折叠

摘要

Abstract

Nε-(1-Carboxyethyl)-L-Lysine (carboxymethyllysine or CML) in food is one of main advanced glycation end-products,which are produced by maillard reaction between reducing sugars and proteins or amino acid.CML has high acid stability and can be used as an important index to evaluate the chemical modification of protein,carbonyl stress and lipid oxidation in maillard reaction of food system.CML can be accumulated in different tissues and organs after entering the human body through a food medium,and would affect the function of tissues and organs in a certain amount.In addition,CML is closely related to many diseases in human body such as diabetes,kidney disease and atherosclerosis,as well as the aging of human organs.The control of CML content in food and the search for safe,efficient and natural CML inhibitors were one of the most research directions at home and abroad for the purpose of avoiding or reducing the harmfulness to human.In this paper,the research progress on formation mechanism and inhibition pathway of CML was reviewed to provide a basis for the effective control of CML content in food.

关键词

羧甲基赖氨酸/危害/形成机理/抑制途径

Key words

Nε-(1-Carboxyethyl)-L-Lysine/harmfulness/formation mechanism/inhibition pathway

引用本文复制引用

韩文凤,谭兴和,林晓丽,邱泼,孟宏昌,贾娟..食品中羧甲基赖氨酸的形成机理和抑制途径研究进展[J].现代食品科技,2018,34(1):245-251,7.

基金项目

河南省高等学校青年骨干教师培养计划项目(2016GGJS-268) (2016GGJS-268)

河南省科技攻关项目(172102110222) (172102110222)

漯河市青年拔尖人才支持计划项目(LBJZ201606) (LBJZ201606)

现代食品科技

OA北大核心CSTPCD

1673-9078

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