保健食品中非法添加药物的广谱筛查和确证OA北大核心CSCDCSTPCD
Rapid screening and confirmation of weight-loss illegally added drugs in health foods
采用液相色谱仪 二极管阵列检测器—离子阱—飞行时间串联质谱仪(LCMS-DAD-IT-TOF)建立减肥类非法添加药物高分辨质谱数据库.样品经乙腈超声提取,提取液经QuEChERS吸附剂净化,以ZORBAX Eclipse AAA色谱柱(150 mm×4.6 mm,4.5μm)分离,乙腈和0.1％乙酸为流动相梯度洗脱.筛查限为0.10～0.75 mg/kg,平均回收率在49.4％～88.1％;相对标准偏差为5.0～14.8％.该方法通过紫外光谱确定…查看全部>>
The high resolution mass spectrometry database of weightloss illegally added drugs was established base on liquid chromatography-diode array detector-ion trap-time of flight tandem mass spectrometry (LC-DAD-MS-IT TOF).The analytes in samples were extracted with acetonitrile and the extract was purified with the mixed QuEChERS sorbents.In the chromatographic analysis,target compounds were separated on a ZORBAX Eclipse AAA column (150 mm × 4.6 mm,4.5 μm) with …查看全部>>
张帆;王美玲;李蓉娟;颜鸿飞;张莹;黄志强
湖南省检验检疫科学研究院,湖南长沙410004长沙环境保护职业技术学院,湖南长沙410004湖南省检验检疫科学研究院,湖南长沙410004中南大学,湖南长沙410083东港出入境检验检疫局,辽宁东港118300湖南省检验检疫科学研究院,湖南长沙410004
保健食品非法添加药物筛查离子阱飞行时间串联质谱
Health foodsillegally added drugsscreeningliquid chromatography-ion trap-time of flight tandem mass spectrometry (LC-MS-IT-TOF)
《食品与机械》 2017 (11)
52-56,5
国家质检总局科技计划项目(编号:2016IK119)“十二五”国家科技支撑计划项目(编号:2012BAK08B01)
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