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刺梨金银花速溶茶珍对化学性肝损伤的保护作用

向红霞 张硕 刘佳 孟小夏 张敏 王鹏娇 高秀丽

食品工业科技2018,Vol.39Issue(3):320-323,329,5.
食品工业科技2018,Vol.39Issue(3):320-323,329,5.DOI:10.13386/j.issn1002-0306.2018.03.061

刺梨金银花速溶茶珍对化学性肝损伤的保护作用

The protective effect of Roxburghii honeysuckle instant tea on chemical liver injury

向红霞 1张硕 1刘佳 2孟小夏 1张敏 3王鹏娇 1高秀丽3

作者信息

  • 1. 贵州医科大学,贵州贵阳550025
  • 2. 贵州省疾控预防控制中心,贵州贵阳550004
  • 3. 贵州医科大学微生物与生化药学工程中心,贵州贵阳550025
  • 折叠

摘要

Abstract

To explore the protective effect on chemical liver injury of Roxburghii honeysuckle instant tea.Methods:SD rats were divided into 6 groups:blank group,model group,solvent group and Roxburghii honeysuckle instant tea with low does group,middle does group,high does group.Each group was ntragastric administration for 30d,the acute hepatic injury model was made by maize oil contraining 2% CCl4 except the control group,the level of ALT,AST and MDA were detected and pathology were carried out.Result:Compared with bank group,the levels of ALT,AST were significantly increased (p < 0.001),the content of MDA was obviously increased (p < 0.05) in model group,indicating that the model of CCl4 intragastric administrasion was successful.Compared with the model group,the activities of AST,ALT were reduced markdely(p < 0.001),the content of MDA were decreased visibly(p < 0.05) in Roxburghii honeysuckle instant tea high-does,medium-does and low-does groups.The total pathological scores were decreased observably (p < 0.01),the ballooning degeneration reduced notable difference (p <0.05),the hepatic necrosis remarkably decreased (p < 0.001),the other types of lesions had improved with varying degrees in each dose group.Conclusion:Roxburghii honeysuckle instant tea had protection effect on chemical liver injury.

关键词

刺梨金银花速溶茶珍/化学性肝损伤/四氯化碳

Key words

Roxburghii honeysuckle instant tea/liver injury/CCl4

分类

轻工纺织

引用本文复制引用

向红霞,张硕,刘佳,孟小夏,张敏,王鹏娇,高秀丽..刺梨金银花速溶茶珍对化学性肝损伤的保护作用[J].食品工业科技,2018,39(3):320-323,329,5.

基金项目

贵州省普通高等学校工程研究中心建设项目(黔教合KY字[2015]338) (黔教合KY字[2015]338)

黔西南特色产业扶贫与生态修复协同创新项目. ()

食品工业科技

OA北大核心CSTPCD

1002-0306

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