中国食品学报2018，Vol.18Issue(2)：63-70,8.DOI:10.16429/j.1009-7848.2018.02.008
荞麦粉对高脂血症小鼠血脂和肝脏抗氧化功能的调节作用
Regulation Function of Buckwheat on Blood Lipid and Liver Anti-Oxidation of Hyperlipemia Mice
摘要
Abstract
Objective:To study the regulation of buckwheat on blood lipid and liver antioxidant in hyperlipemia mice.Method:Male C57 mice were divided into normal diet,hyperlipemia,and treatments groups.The treatments were carried out by 10 kinds of buckwheat under the condition of high-fat diet,with 10 mice in each group.Blood and liver samples were collected after 12 weeks.The levels of total cholesterol (TC),triglycerides (TG),high density lipoprotein cholesterol (HDL-C),and low density lipoprotein cholesterol (LDL-C) in the serum were measured.The content of malondialdehyde (MDA) as well as the activities of total superoxide dismutase (SOD) and glutathione peroxidase (GPH-Px) were determined,and the pathological sections of the liver tissues were observed.Results:It was found that mice in all the buckwheat treated groups had lower body weights and decreased liver indexes when compared with mice in pure hyperlipemia group.The concentrations of TC,TG,and LDL-C in the serum were decreased,and the concentration of HDL-C was increased.Buckwheat improved GSH-Px and SOD activities of liver,and reduce the MDA concentration significantly (P＜0.05) in hypedipemia mice.Meanwhile,the cellular arrangement,the outline and funicular structures of liver in hypedipemia mice were improved by the addition of buckwheat.Moreover,the results showed that the improvement of blood lipid and antioxidant activity by tartary buckwheat was better than that by common buckwheat.Conclusion:Buckwheat has the positive effects in reducing blood lipids,enhancing liver antioxidant capacities and improving lipid metabolism of liver,thus has potential functions in the protection of liver.关键词
荞麦粉/高脂血痘/血脂调节/抗氧化作用Key words
buckwheat/hyperlipidemia/lipid regulation/antioxidant effect引用本文复制引用
綦文涛,王世霞,李笑蕊,贠婷婷,苗海江,李爱科..荞麦粉对高脂血症小鼠血脂和肝脏抗氧化功能的调节作用[J].中国食品学报,2018,18(2):63-70,8.基金项目
粮食公益性行业科研专项(201313006-5) （201313006-5）
