中国食物与营养2018，Vol.24Issue(1)：69-71,79,4.
益生菌对肥胖儿童和青少年非酒精脂肪肝的影响
Effects of Probiotics on Nonalcoholic Fatty Liver Disease in Obese Children and Adolescents
魏玲 1娄健1
作者信息
- 1. 云南省第二人民医院营养科,昆明650021
- 折叠
摘要
Abstract
[Objective] To evaluate the effects of some probiotics on biochemical and sonographic of nonalcoholic fatty liver disease (NAFLD).[Method] This randomized triple-blind trial was conducted among 64 obese children with sonographic NAFLD.They were randomly allocated to receive probiotic capsule or placebo for 12 weeks.[Result] After intervention,in the probiotic group the mean levels of alanine aminotransferase decreased from 32.8 ± 19.6 to 23.1 ± 9.5 U/L (P =0.002) and mean aspartate aminotransferase decreased from 32.2 ± 15.7 to 24.3 ±7.7 U/L (P =0.002).Likewise the mean cholesterol,low-density lipoprotein-C and trigtycerides as well as waist circumference decreased in the intervention group,without significant change in weight,body mass index and body mass index z score.In the placebo group,there was no significant change in the indexes befor and after the study.MAfter the trial,normal liver sonography was reported in 17 (53.12％)and 5 (15.62％) of patients in the intervention and placebo groups,respectively.[Conclusion] The present findings suggest that a course of the abovementioned probiotic compound can be effective in improving pediatric NAFLD.关键词
青少年/儿童/非酒精性脂肪肝/肥胖/益生菌Key words
adolescent/children/nonalcoholic fatty liver disease (NAFLD)/obesity/probiotics引用本文复制引用
魏玲,娄健..益生菌对肥胖儿童和青少年非酒精脂肪肝的影响[J].中国食物与营养,2018,24(1):69-71,79,4.
