食品与机械2017，Vol.33Issue(10)：1-5,5.DOI:10.13652/j.issn.1003-5788.2017.10.001
人源乳酸菌耐酸耐胆盐能力及降胆固醇作用研究
Ability of acid and bile salt resistance of lactic acid bacteria and its cholesterol lowering effect from human origin
摘要
Abstract
Lactic acid bacteria (LAB) with ability of acid and bile salt resistance were isolated from the feces of the longevity population in Rugao by using selective medium,artificial gastric juice and bile salt medium,and the ability of cholesterol reducing and manner were studied.The results showed that the survival rate of all isolated 60 strains of LAB in the pH 3.0 artificial gastric juice was more than 30％,the LAB from the middle-aged group,elderly group and longevity group was significantly higher than that in the youth group (P＜0.05);the survival rate of LAB in the 0.3％ and 0.5％ bile salt culture medium was more than 20％,of which the LAB in elderly group and longevity group was significantly higher than that of youth group and middle-aged group (P＜0.05).The ability of cholesterol lowering of the LAB from the longevity group was significantly higher than that of middle-aged group (P＜0.05),the ability of cholesterol reducing of lactobacillus spp.and Weissella spp.was significantly higher than that of Enterococcus spp.(P＜0.05),the main manners of cholesterol lowering of LAB were cell absorption and sedimentation.The LAB come from longevity population have the strong ability of acid and bile salt resistance and cholesterol lowering,and the longevity group are higher than others from other age groups.关键词
乳酸菌/降胆固醇/耐酸耐胆盐/长寿地区/年龄组Key words
longevity area/age groups/Lactic acid bacteria/acid and bile salt resistance/cholesterol lowering引用本文复制引用
陈大卫,顾瑞霞,鲁茂林,黄玉军,张臣臣,关成冉,张玉律,范晨雨..人源乳酸菌耐酸耐胆盐能力及降胆固醇作用研究[J].食品与机械,2017,33(10):1-5,5.基金项目
国家自然科学基金青年基金项目(编号:31701627) （编号:31701627）
国家自然科学基金基金面上项目(编号:31571855) （编号:31571855）
江苏省高校自然科学研究面上项目(编号:17KJB550009) （编号:17KJB550009）
江苏省高校自然科学研究重大项目(编号:17KJA550004) （编号:17KJA550004）
江苏省乳品生物技术与安全控制重点实验室开放课题(编号:K14003) （编号:K14003）
