食品科学2018，Vol.39Issue(5)：234-238,5.DOI:10.7506/spkx1002-6630-201805035
水飞蓟油的体外抗氧化活性及对氧化损伤小鼠的保护作用
Antioxidant Activity in Vitro of Silybum marianum Seed Oil and Its Protective Effect on Oxidative Damage in Mice
摘要
Abstract
Objective:To investigate the antioxidant activity in vitro and the protective effect of Silybum marianum seed oil on oxidative damage induced by D-galactose in mice.Methods:The scavenging capacity for DPPH and hydroxyl radicals and the total antioxidant capacity were determined to explore in vitro antioxidant activity of the seed oil.Furthermore,the effects of the seed oil on serum antioxidant enzyme activities and liver morphology were examined to evaluate its protective effect on oxidative damage in mice.Results:Silybum marianum seed oil had antioxidant capacity in vitro in a dose-dependent manner.It could significantly increase the activities of superoxide dismutase (SOD),glutathione peroxidase (GSH-Px) and total antioxidant capacity (T-AOC) in mice serum and protect the integrity of liver cell morphology in mice.Conclusion:Silybum marianum seed oil has antioxidant activity in vitro and possesses a protective effect on D-galactose-induced oxidative damage in mice.关键词
水飞蓟油/体外抗氧化/氧化损伤/抗氧化酶Key words
Silybum marianum seed oil/in vitro antioxidant activity/oxidative damage/antioxidant enzyme分类
轻工纺织引用本文复制引用
朱淑云,周越,肖香,董英,朱胜虎..水飞蓟油的体外抗氧化活性及对氧化损伤小鼠的保护作用[J].食品科学,2018,39(5):234-238,5.基金项目
江苏省高校自然科学研究面上项目(16KJB550001) （16KJB550001）
江苏省博士后科研资助计划项目(1601058A) （1601058A）
