食品工业科技2018，Vol.39Issue(9)：325-331,341,8.DOI:10.13386/j.issn1002-0306.2018.09.057
多糖对免疫系统调控的研究进展
Research progress on the immune regulation of polysaccharides related to immune system
摘要
Abstract
Polysaccharides,as a kind of important biological information macromolecules,have been indicated to exist widely in animals,plants and microbials.Currently,the role of polysaccharides in regulating immune system has been generally recognized by the academic community.The immunoregulatory mechanism of polysaccharides on the immune system was mainly via binding to pattern recognition receptors on the surface of immune cells such as Toll like receptors,mannose receptor,Dectin-1,scavenger receptors and complement receptors.Thus stimulating immune cells involves protomoting the phagocytosis of macrophages,regulating the proliferation and transformation of lymphocyte,enhancing the activation of complement system and inducing the secretion of cytokines so as to achieve the immunoregnlatory effects.In addition,the regulation of neuroendocrineimmunoregulatory network is regarded as a vital way to exert immunoregulatory effects of polysaccharides as well.The biological activity of polysaccharide and its immunomodulatory effects have always been one of the hot projects.The aim of this article was to review the effects and mechanisms of polysaccharides on immunoregulatory effects related to immune system.关键词
多糖/免疫调控/免疫系统/免疫应答机制Key words
polysaccharides/immunoregulation/immune system/immune response mechanism分类
轻工纺织引用本文复制引用
汤小芳,刘想,胡美华,张贤益,李文娟..多糖对免疫系统调控的研究进展[J].食品工业科技,2018,39(9):325-331,341,8.基金项目
国家自然科学基金项目(31560460) （31560460）
江西省自然科学基金项目(20151BAB204038,20171ACB21016) （20151BAB204038,20171ACB21016）
食品科学与技术国家重点实验室青年研究基金项目(SKLF-QN-201509). （SKLF-QN-201509）
