茶叶科学2018，Vol.38Issue(3)：221-226,6.
普洱茶安全性毒理学评价研究概述
Review on the Studies about Safety Assessment of Pu-erh Tea
摘要
Abstract
Toxicology assessment is an important index to evaluate food safety. To provide scientific references for the evaluation of safety of Pu-erh tea, relative studies were reviewed. The acute oral toxicity tests showed that the LD50 of Pu-erh tea was great than 5000 mg·kg-1, which belonged to the actual non-toxic level. The no-observed-adverse-effect-levels of non-fermented and post-fermented Pu-erh tea were 1250 mg·kg-1·d-1 and 5000 mg·kg-1·d-1 in 28 d or 90 d administration tests. Pu-erh tea showed no mutagenicity on the primitive, authentic and reproductive cells during genetic toxicity evaluation. The no-observed-adverse-effect level of Pu-erh tea was 700 mg·kg-1·d-1 for both reproductive and developmental toxicities. Little or none toxicity of Pu-erh tea to mice liver cells was observed. No pathological change was observed in human acute and subacute toxicity assays. In conclusion, the toxicology assessments proved the safety of Pu-erh tea.关键词
食品安全性/毒理学评价/普洱茶Key words
food safety/toxicological assessment/Pu-erh tea分类
轻工纺织引用本文复制引用
马燕,陈立佼,吕才有,赵明..普洱茶安全性毒理学评价研究概述[J].茶叶科学,2018,38(3):221-226,6.基金项目
国家自然科学基金项目(31560221,31760225)、国家农业产业技术体系茶叶专项(CARS-19) （31560221,31760225）
