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几种茶多糖降血糖活性的研究

刘丹奇 任发政 李景明 侯彩云

茶叶科学2019,Vol.39Issue(6):652-660,9.
茶叶科学2019,Vol.39Issue(6):652-660,9.

几种茶多糖降血糖活性的研究

Comparative Study on the Structure and Hypoglycemic Activity of Several Tea Polysaccharides

刘丹奇 1任发政 1李景明 2侯彩云2

作者信息

  • 1. 北京食品营养与人类健康高精尖创新中心,中国农业大学食品科学与营养工程学院,北京 100083
  • 2. 食品质量安全北京实验室,中国农业大学食品科学与营养工程学院,北京 100083
  • 折叠

摘要

Abstract

To study and compare the composition, blood sugar lowering effect and composition of WTP, GTP and BTP. Shoumei, Longjing and Bailingongfu were selected as representatives of white tea, green tea and black tea, and the composition, molecular weight of tea polysaccharides were determined. The mice diabetes model was induced by streptozotocin, metformin was used as a positive control to study the hypoglycemic effect of tea polysaccharides, and qPCR was used to determine the expression level of related genes in mice liver. The results showed that the molecular weights of WTP, GTP and BTP are 18 180 Da, 19 470 Da and 8 745 Da, respectively. The selected tea polysaccharides have hypoglycemic effect, the fasting blood glucose decline rates of WTP, GTP and BTP were 53.2%, 52.8% and 61.6%, respectively. Tea polysaccharides can all improve glucose tolerance, down-regulate the expression of Foxo1, G6Pc, PEPCK and TXNIP genes in mice and there are some differences.

关键词

茶多糖/降血糖/糖代谢

Key words

tea polysaccharides/hypoglycemic/sugar metabolism

分类

轻工纺织

引用本文复制引用

刘丹奇,任发政,李景明,侯彩云..几种茶多糖降血糖活性的研究[J].茶叶科学,2019,39(6):652-660,9.

基金项目

北京食品营养与人类健康高精尖创新中心开放基金项目 ()

茶叶科学

OA北大核心CSCDCSTPCD

1000-369X

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