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提高益生菌耐加工贮藏稳定性和体内存活率的递送系统研究进展

朱荻 李媛 陈莎男 梅晓宏 岳庆 常茹欣 李星 刘斌 张华磊 韩小龙

食品科学2023,Vol.44Issue(21):1-13,13.
食品科学2023,Vol.44Issue(21):1-13,13.DOI:10.7506/spkx1002-6630-20230609-079

提高益生菌耐加工贮藏稳定性和体内存活率的递送系统研究进展

Advances in the Delivery Systems for Improving the Processing Stability,Storage Stability and in Vivo Survival Rate of Probiotics

朱荻 1李媛 1陈莎男 1梅晓宏 1岳庆 1常茹欣 1李星 1刘斌 1张华磊 2韩小龙2

作者信息

  • 1. 中国农业大学食品科学与营养工程学院,食品胶体与营养递送研究中心,北京 100083
  • 2. 山东中科嘉亿生物工程有限公司,山东 潍坊 262500
  • 折叠

摘要

Abstract

Probiotics offer numerous health benefits for human beings.However,it is difficult to achieve the expected beneficial effects of oral probiotics due to the viability loss during processing,storage and digestion.Oral delivery systems are effective ways to improve the processing and storage stability,gastric acid and bile salt tolerance,and intestinal adhesion and colonization ability of probiotics.This review focuses on the state of the art of oral delivery of probiotics,and summarizes the types of probiotics commonly used in probiotic products and their functional characteristics.Specifically,this review analyzes the effects of external environmental factors such as humidity,temperature,pH and oxygen,and internal environments such as the mouth,stomach,and small intestine on the survival rate of probiotics.Furthermore,the characteristics and applications of different oral delivery systems including microcapsule,hydrogel,oleogel,nanocoating,emulsion,and nanofiber are compared.Finally,this review proposes future prospects for cost reduction,intelligent packaging,co-packaging and population experiments of probiotic delivery systems,with the aim of providing technical support for the development of probiotic formulations with high storage stability and high viability suitable for intestinal targeted delivery.

关键词

益生菌/封装/递送系统/微胶囊/活菌数/肠道定植

Key words

probiotics/encapsulation/delivery system/microcapsule/viable count/intestinal colonization

分类

轻工纺织

引用本文复制引用

朱荻,李媛,陈莎男,梅晓宏,岳庆,常茹欣,李星,刘斌,张华磊,韩小龙..提高益生菌耐加工贮藏稳定性和体内存活率的递送系统研究进展[J].食品科学,2023,44(21):1-13,13.

基金项目

国家自然科学基金面上项目(32172345) (32172345)

食品科学

OA北大核心CSCDCSTPCD

1002-6630

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