食品工业科技2024，Vol.45Issue(2)：364-372,9.DOI:10.13386/j.issn1002-0306.2023020189
十字花科植物萝卜硫素生理功能及其产品应用的研究进展
Research Progress on the Physiological Function and Product Application of Sulforaphane in Cruciferous Plants
摘要
Abstract
Raphasatin,also known as sulforaphane,is primarily found in vegetables of the Brassicaceae family,specifically those of the Raphanus and Brassica genera.It is an isothiocyanate compound produced by the hydrolysis of glucosinolates under the action of endogenous myrosinase enzymes.Raphasatin was shown to have the strongest anticancer properties among vegetables,demonstrating a significant inhibitory effect on various forms of cancer such as breast cancer,liver can-cer,and colon cancer.This paper reviews the stability of raphasatin and methods for its extraction and purification.It expl-ains the mechanisms by which raphasatin protects cells under oxidative stress by inducing the expression of related anti-oxidant proteins and detoxifying enzymes,and how it alleviates or suppresses inflammation through involvement in NF-κB signaling pathway.Additionally,it explores its physiological functions in preventing and treating Helicobacter pylori infections,lung bacteria,mental disorders,and neurodegenerative diseases,etc.Furthermore,the paper summarizes the current status and prospects of raphasatin products in the fields of biomedicine,health supplements,and food,providing a reference for the scientific research and application of raphasatin.关键词
十字花科/萝卜硫素/提取纯化/氧化应激/抗炎症/生理功能/产品应用Key words
Brassicaceae/sulforaphane/extraction and purification/protection of oxidative stress/anti-inflammatory/phy-siologic function/product application分类
轻工纺织引用本文复制引用
孙奕良,李海燕,洪汉君,马志敏,王秀丽,朱映红,梅振武..十字花科植物萝卜硫素生理功能及其产品应用的研究进展[J].食品工业科技,2024,45(2):364-372,9.基金项目
中国农业科学院科技创新工程-食物消费行为和食物营养成分对慢病的作用及科普干预效果研究(ASTIP2023A-5). （ASTIP2023A-5）
