猪苓汤化学成分及效应机制研究进展OACSTPCD
Research progress on chemical constituents and mechanism of Zhuling decoction
猪苓汤已广泛应用于肾病综合征、慢性肾炎、尿路结石、泌尿系感染、慢性肾小球肾炎等疾病的治疗,并取得了显著疗效.现代研究表明,猪苓汤具有利尿、改善肾脏局部炎症、改善肾功能、抑制肾结石形成等作用.现通过查阅相关文献,从化学成分及药理效应分子机制方面对猪苓汤研究现状进行综述,以期为该方创新药物开发及临床适应证的分析研究提供参考.
Zhuling decoction has been widely used in the treatment of nephrotic syndrome,chronic nephritis,u-rinary calculi,urinary tract infection,chronic glomerulonephritis and other diseases,and has achieved remarkable cur-ative effect.Modern studies have shown that Zhuling decoction has the effects of diuresis,improving renal local in-flammation,improving renal function,and inhibiting renal calculi formation.This paper reviews the research status of Zhuling decoction from the aspects of chemical composition and pharmacological effect molecular mechanism,in order to provide reference for the development of innovative drugs and the analysis of clinical indications.
张蒙蒙;翟文生;张佳伟;柴二曦
河南中医药大学儿科医学院,河南 郑州 450000河南中医药大学第一附属医院,河南 郑州 450000
药学
猪苓汤化学成分药理作用效应机制肾病综合征慢性肾炎
Zhuling decoctionChemical constituentsEffect mechanismClinical applicationNephrotic syn-dromeChronic nephritis
《陕西中医》 2024 (001)
143-145 / 3
国家自然科学基金资助项目(81873339)
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