中国中医药信息杂志2024，Vol.31Issue(1)：180-184,5.DOI:10.19879/j.cnki.1005-5304.202212116
中药基于血管生成微环境防治胃癌前病变研究进展
Research Progress in TCM for Prevention and Treatment of Precancerous Lesions of Gastric Cancer Based on Angiogenesis Microenvironment
摘要
Abstract
The angiogenic microenvironment is a new blood vessel with different molecular and functional characteristics that sprouts on the original blood vessels through different mechanisms,which directly affects the process of tumor cell growth,proliferation,and migration and has an important impact on the occurrence and development of precancerous lesions of gastric cancer.Correa mode has shown that precancerous lesions of gastric cancer is the key pathological stage before the occurrence of gastric cancer,and it is of great significance to advance the prevention and treatment strategy to this stage.TCM believes that qi deficiency and blood stasis is the key pathogenesis of precancerous lesions of gastric cancer,and its basic treatment is to replenish qi and remove blood stasis,and based on the syndrome differentiation,drugs with the efficacy of nourishing yin and tonifying stomach,soothing the liver and regulating qi,resolving phlegm and dispersing lumps,and clearing heat and dampness for treatment.This article discussed the correlation between precancerous lesions of gastric cancer and angiogenic microenvironment and its regulatory pathways,and summarized the methods and mechanisms of TCM in the treatment of precancerous lesions of gastric cancer from the perspective of regulating angiogenic microenvironment-related pathways,in order to provide a reference for the treatment of precancerous lesions of gastric cancer with TCM.关键词
胃癌前病变/血管生成微环境/中药治疗/综述Key words
precancerous lesions of gastric cancer/angiogenesis microenvironment/TCM treatment/review分类
医药卫生引用本文复制引用
封壮壮,豆鹏程,宋瑞平,陈心怡,王娟娥,高瑞瑞,王晓龙,舒劲..中药基于血管生成微环境防治胃癌前病变研究进展[J].中国中医药信息杂志,2024,31(1):180-184,5.基金项目
国家自然科学基金(82060860) （82060860）
甘肃省自然科学基金(21JR7RA588) （21JR7RA588）
