食品科学2023，Vol.44Issue(23)：240-251,12.DOI:10.7506/spkx1002-6630-20221111-124
细菌芽孢萌发分子机制研究进展
Progress in Understanding the Molecular Mechanism of Bacterial Spore Germination
摘要
Abstract
In response to nutrient limitation,Bacillus and Clostridium can form metabolically dormant spores,which are extremely resistant to a variety of environmental stresses.The ubiquitousness of spores in the environment makes it inevitable for them to enter the food processing chain.Once suitable conditions are available,spores will rapidly germinate to resume vegetative growth,thereby causing food spoilage.Since germination induces the loss of stress resistance in dormant spores,germination-inactivation strategy has been developed to mildly kill spores while maintaining food quality.Understanding the spore germination process of diverse bacterial species,the related signal transduction mechanism and the factors impacting the germination process are beneficial to develop efficient and precise strategies for inducing spore germination and raising the efficiency of inactivation,which is of great significance to the control of spores in foods.This review describes the mechanisms of the spore germination of Bacillus subtilis,Clostridium perfringens and C.difficile in terms of spore germination receptor activation and signal transduction.Moreover,inducers and inhibitors of spore germination of diverse bacterial species are also comprehensively summarized.This review provides a theoretical foundation for effectively controlling bacterial spores in foods and ensuring food quality.关键词
杆菌芽孢/梭菌芽孢/萌发机制/萌发因子/萌发受体/信号传导Key words
Bacillus spores/Clostridium spores/germination mechanism/germinant/germination receptors/signal transduction分类
轻工业引用本文复制引用
张天宇,吕风至,桂萌,吴晓蒙,赵靓,王永涛,饶雷,廖小军..细菌芽孢萌发分子机制研究进展[J].食品科学,2023,44(23):240-251,12.基金项目
国家自然科学基金青年科学基金项目(32001658) （32001658）
农业科研杰出人才培养计划项目(13210317) （13210317）
