食品科学2023，Vol.44Issue(23)：365-371,7.DOI:10.7506/spkx1002-6630-20221210-103
肠道中有益菌培养组学的研究进展
Progress in Culturemics Research on Beneficial Intestinal Bacteria
摘要
Abstract
Gut microbes especially the beneficial ones play an important role in maintaining human health.At present,the research methods for intestinal microbes are mainly based on non-culture technologies such as metagenomics.The relationship between intestinal microbes and the body's health can be found by using metagenomic sequencing technology.Researchers have found that most of the bacteria in the gut are uncultured,and their molecular mechanisms of action are unclear.Culturomics can be used to successfully isolate and culture some intestinal bacteria difficult to culture by improving the composition of culture medium and optimizing the culture conditions.The application of culturomics provides technical support for research on the functions of intestinal bacteria in the host and further screening of beneficial intestinal bacteria.Therefore,using culturomics technology to cultivate more beneficial intestinal bacteria and studying their phenotypes and gene functions are future research priorities.This article reviews the culturomics of and the cultivation methods for intestinal beneficial bacteria for the purpose of providing a reference for the cultivation of beneficial intestinal microorganisms for human health.关键词
培养组学/肠道微生物/培养方法/乳酸菌/双歧杆菌Key words
culturomics/gut microbes/culture methods/lactic acid bacteria/Bifidobacterium分类
生物学引用本文复制引用
玉霞,赵飞燕,孙志宏..肠道中有益菌培养组学的研究进展[J].食品科学,2023,44(23):365-371,7.基金项目
内蒙古自治区自然科学基金重大项目(2020ZD12) （2020ZD12）
