低氧运动对肥胖成人身体成分和胰岛素抵抗影响的Meta分析OA

Abs tract:Objective To quantitatively evaluate the efficacy of hypoxic exercise on body composition and insulin resistance in obese adults through Meta-analysis.Methods Randomized controlled trials related to hypoxic exercise and obesity were searched in Chinese and English databases,and Stata14.0 was used for data analysis.Results A total of 24 documents and 548 subjects were included in the study.Meta-analysis results show that compared with normoxic exercise,hypoxic exercise has significant advantages in reducing the weight of obese people(WMD=-1.60,p<0.05)and reducing body fat rate(WMD=-1.21,p<0.01).Hypoxic exercise has a small effect size on improving insulin resistance(ES=-0.22),fasting insulin(WMD=-0.24)and HbA1c(WMD=-0.27),and no significant difference in improving fasting blood glucose(WMD=-0.03).Adjusting variable results,that exercise between 1,500 and 3,500 m has the most obvious effect on improving body weight and body fat rate(WMD=-1.60,p<0.05;WMD=-1.21,p<0.01).Above≥4 weeks of exercise has the most obvious effect on improving body weight and body fat rate(WMD=-1.90,p<0.05;WMD=-1.31,p<0.01).Above≥300 hours per week has the most obvious effect on improving body weight and body fat rate(WMD=-1.92,p<0.05;WMD=-1.41,p<0.01).Conclusion Hypoxic exercise can significantly improve body composition in obese individuals.Exercising at a plateau of 1,800～3,500 m or hypoxic environment at the same altitude,at least 4 weeks and at least 300 hours per week,has the best effect on improv-ing the body composition of obese people.