食品工业科技2024，Vol.45Issue(3)：123-129,7.DOI:10.13386/j.issn1002-0306.2023050025
基于右旋糖酐酶制备小麦多孔淀粉及其特性
Wheat Porous Starch:Preparation and Characteristics with Dextranase-Catalyzed Rotation
摘要
Abstract
The preparation of porous starch by biological enzyme method is mild conditions,simple process,and environmentally sustainable.This study employed a dextranase with specific hydrolysis of α-1,6-glycosidic bonds ability to prepare porous wheat starch.The structure of the starch was analyzed by X-ray diffraction,Fourier-transform infrared spectroscopy,scanning electron microscopy,and particle size analysis.The rates of starch swelling,oil and water absorption,and drug loading,as well as solubility,were measured.The results showed the formation of pores on the starch surface after treatment at 50℃for 16 h,together with reduced particle sizes,while the crystal structure of the starch did not change significantly.The specific volume of the porous starch was 2.11±0.02 cm3/g,and the solubility was 9.02%±0.21%.Swelling reached 9.91%±0.22%while the water and oil absorption rates were increased to 80.12%and 78.23%,respectively.The loading rates of curcumin,dabigatran mesylate,nystatin,and ofloxacin in a 160:1 ratio reached an average of 75.07%.In vitro experiments showed that the release rate of curcumin loaded onto wheat porous starch was significantly reduced.The release rate in stomach for 2.5 h was approximately 30%,and it was approximately 40%in intestine for 5 h.The research results provided a basis for the preparation and application of wheat porous starch.关键词
小麦淀粉/右旋糖酐酶/多孔淀粉/药物负载Key words
wheat starch/dextranase/porous starch/drug loading分类
轻工纺织引用本文复制引用
王博岩,李强,吴一卓,章均哲,吴旭东,张磊,吕明生,王淑军..基于右旋糖酐酶制备小麦多孔淀粉及其特性[J].食品工业科技,2024,45(3):123-129,7.基金项目
国家自然科学基金(32172154) （32172154）
国家重点研发计划项目(深海新型生物酶制剂创制与产业化,2022YFC2805101). （深海新型生物酶制剂创制与产业化,2022YFC2805101）
