中风与神经疾病杂志2024，Vol.41Issue(1)：3-6,4.DOI:10.19845/j.cnki.zfysjjbzz.2024.0001
外泌体在缺血性卒中诊断及治疗中的研究与应用
Research and application of exosomes in the diagnosis and treatment of ischemic stroke
摘要
Abstract
Ischemic stroke(IS)is the most common type of stroke that can lead to severe neurological dysfunction while effective diagnostic and therapeutic methods are currently limited.Exosomes are natural vesicles that can play a key role in intercellular communication by delivering proteins,lipids,and nucleic acids.Notably,IS could cause changes in the level and content of exosome,which can serve as a potential biomarker to assist the diagnosis and treatment of IS.This article reviews the potential diagnostic value of exosomes,discusses their repair effects,and explores the potential applica-tion as drug carriers in IS.We also provide a concise summary of the current clinical research status based on exosomes.关键词
缺血性卒中/外泌体/诊断/治疗/药物输送Key words
Ischemic stroke/Exosome/Diagnosis/Treatment/Drug delivery分类
医药卫生引用本文复制引用
尹文婧,曲瑒,任佳欣,马虹印,郭珍妮,杨弋..外泌体在缺血性卒中诊断及治疗中的研究与应用[J].中风与神经疾病杂志,2024,41(1):3-6,4.基金项目
吉林大学白求恩医学部(2022JBGS03) （2022JBGS03）
吉林省科技厅(YDZJ202302CXJD061、20220303002SF) （YDZJ202302CXJD061、20220303002SF）
吉林省重点实验室(YDZJ202302CXJD017) （YDZJ202302CXJD017）
