中风与神经疾病杂志2024,Vol.41Issue(1):7-13,7.DOI:10.19845/j.cnki.zfysjjbzz.2024.0002
脑小血管病与卒中防治的"异"与"同"
Differences and similarities in the prevention and treatment of cerebral small vessel disease and stroke
摘要
Abstract
Cerebral small vessel disease is a series of complex and heterogeneous cerebrovascular syndromes caused by various etiological factors that affect small vessels in the brain.Due to a lack of typical symptoms,the diagnosis of cere-bral small vessel disease relies mainly on magnetic resonance imaging,and the neuroimaging findings can include recent small subcortical infarcts,lacunes of presumed vascular origin,white matter hyperintensities of presumed vascular origin,perivascular spaces,cerebral microbleeds,cortical superficial siderosis,and brain atrophy.Currently,the pathogenic mechanism of cerebral small vessel disease remains unclear,and specific treatment is also lacking.Given its similarities with stroke in risk factors and histopathological characteristics,stroke prevention and treatment approaches,such as anti-hypertensive and antiplatelet therapies,can be applied to the treatment of cerebral small vessel disease.However,due to the differences between the two conditions,stroke treatments cannot be fully suitable for cerebral small vessel disease,and an individualized comprehensive assessment is needed.This review presents the management of cerebral small vessel dis-ease and stroke,highlighting their similarities and differences.关键词
脑小血管疾病/卒中/磁共振成像Key words
Cerebral small vessel disease/Stroke/Magnetic resonance imaging分类
医药卫生引用本文复制引用
张枘南,王伊龙..脑小血管病与卒中防治的"异"与"同"[J].中风与神经疾病杂志,2024,41(1):7-13,7.基金项目
国家自然科学基金委员会杰出青年科学基金项目(81825007) (81825007)
北京高校卓越青年科学家计划项目(BJJWZYJH01201910025030) (BJJWZYJH01201910025030)
首都卫生发展科研专项(首发-2022-2-2045) (首发-2022-2-2045)
科技部国家重点研发计划(2022YFF1501500、2022YFF1501501、2022YFF1501502、2022YFF1501503、2022YFF1501504、2022YFF1501505) (2022YFF1501500、2022YFF1501501、2022YFF1501502、2022YFF1501503、2022YFF1501504、2022YFF1501505)
青年北京学者(010) (010)
口腔健康北京实验室(PXM2021_014226_000041) (PXM2021_014226_000041)