脑小血管病与卒中防治的"异"与"同"OACSTPCD

Cerebral small vessel disease is a series of complex and heterogeneous cerebrovascular syndromes caused by various etiological factors that affect small vessels in the brain.Due to a lack of typical symptoms,the diagnosis of cere-bral small vessel disease relies mainly on magnetic resonance imaging,and the neuroimaging findings can include recent small subcortical infarcts,lacunes of presumed vascular origin,white matter hyperintensities of presumed vascular origin,perivascular spaces,cerebral microbleeds,cortical superficial siderosis,and brain atrophy.Currently,the pathogenic mechanism of cerebral small vessel disease remains unclear,and specific treatment is also lacking.Given its similarities with stroke in risk factors and histopathological characteristics,stroke prevention and treatment approaches,such as anti-hypertensive and antiplatelet therapies,can be applied to the treatment of cerebral small vessel disease.However,due to the differences between the two conditions,stroke treatments cannot be fully suitable for cerebral small vessel disease,and an individualized comprehensive assessment is needed.This review presents the management of cerebral small vessel dis-ease and stroke,highlighting their similarities and differences.