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脑小血管病与卒中防治的"异"与"同"

张枘南 王伊龙

中风与神经疾病杂志2024,Vol.41Issue(1):7-13,7.
中风与神经疾病杂志2024,Vol.41Issue(1):7-13,7.DOI:10.19845/j.cnki.zfysjjbzz.2024.0002

脑小血管病与卒中防治的"异"与"同"

Differences and similarities in the prevention and treatment of cerebral small vessel disease and stroke

张枘南 1王伊龙1

作者信息

  • 1. 首都医科大学附属北京天坛医院神经病学中心,北京脑科学与类脑研究所,国家神经疾病医学中心,首都医科大学人脑保护高精尖创新中心,国家神经系统疾病临床医学研究中心,口腔健康北京实验室,临床流行病学北京市重点实验室,北京 100070
  • 折叠

摘要

Abstract

Cerebral small vessel disease is a series of complex and heterogeneous cerebrovascular syndromes caused by various etiological factors that affect small vessels in the brain.Due to a lack of typical symptoms,the diagnosis of cere-bral small vessel disease relies mainly on magnetic resonance imaging,and the neuroimaging findings can include recent small subcortical infarcts,lacunes of presumed vascular origin,white matter hyperintensities of presumed vascular origin,perivascular spaces,cerebral microbleeds,cortical superficial siderosis,and brain atrophy.Currently,the pathogenic mechanism of cerebral small vessel disease remains unclear,and specific treatment is also lacking.Given its similarities with stroke in risk factors and histopathological characteristics,stroke prevention and treatment approaches,such as anti-hypertensive and antiplatelet therapies,can be applied to the treatment of cerebral small vessel disease.However,due to the differences between the two conditions,stroke treatments cannot be fully suitable for cerebral small vessel disease,and an individualized comprehensive assessment is needed.This review presents the management of cerebral small vessel dis-ease and stroke,highlighting their similarities and differences.

关键词

脑小血管疾病/卒中/磁共振成像

Key words

Cerebral small vessel disease/Stroke/Magnetic resonance imaging

分类

医药卫生

引用本文复制引用

张枘南,王伊龙..脑小血管病与卒中防治的"异"与"同"[J].中风与神经疾病杂志,2024,41(1):7-13,7.

基金项目

国家自然科学基金委员会杰出青年科学基金项目(81825007) (81825007)

北京高校卓越青年科学家计划项目(BJJWZYJH01201910025030) (BJJWZYJH01201910025030)

首都卫生发展科研专项(首发-2022-2-2045) (首发-2022-2-2045)

科技部国家重点研发计划(2022YFF1501500、2022YFF1501501、2022YFF1501502、2022YFF1501503、2022YFF1501504、2022YFF1501505) (2022YFF1501500、2022YFF1501501、2022YFF1501502、2022YFF1501503、2022YFF1501504、2022YFF1501505)

青年北京学者(010) (010)

口腔健康北京实验室(PXM2021_014226_000041) (PXM2021_014226_000041)

中风与神经疾病杂志

OACSTPCD

1003-2754

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