中国防痨杂志2024，Vol.46Issue(2)：165-172,8.DOI:10.19982/j.issn.1000-6621.20230395
高负担地区肺结核密切接触者中结核分枝杆菌潜伏感染者预防性治疗接受意愿及影响因素研究
Analysis of willingness of receiving preventive treatment in patients with latent tuberculosis infection among close contacts of pulmonary tuberculosis in high-burden areas
摘要
Abstract
Objective:To understand the willingness of accepting tuberculosis preventive treatment(TPT)and its influencing factors among patients with latent tuberculosis infection(LTBI)in tuberculosis high-burden areas of Xinjiang Uygur Autonomous Region and to provide evidence for policy making.Methods:A cross-sectional study was conducted to select 3023 patients with tuberculosis confirmed in Awati County and Wushi County,Aksu Prefecture,Xinjiang Uygur Autonomous Region,from August 1,2021 to December 31,2022,as index cases,then 6407 close contacts of index cases were screened for LTBI after which 529 LTBI patients were identified.A questionnaire survey was conducted on the willingness of accepting TPT.Information on population characteristics,daily habits,living environment,contact information,health status was collected too.516 valid questionnaires were retrieved.A binomial-logit linked generalized linear model was constructed to explore the influencing factors.Results:497 cases were willing to receive TPT,with an acceptance rate of 96.32％(497/516).Those LTBI patients who do not live together with the indicated case were more likely to receive preventive treatment(OR=5.713,95％CI:1.477-22.097),and those who do not contact other tuberculosis patients except the indicated case were more likely to refuse preventive treatment(OR=0.142,95％CI:0.039-0.516).Conclusion:LTBI patients among close contacts in high tuberculosis burden areas have a high willingness to receive TPT,which is influenced by their own economic level and contact with tuberculosis patients.关键词
分枝杆菌,结核/分枝杆菌感染/问卷调查/因素分析,统计学Key words
Mycobacterium tuberculosis/Mycobacterium Infections/Questionnaires/Factor analysis,statistical分类
医药卫生引用本文复制引用
张静,付若楠,王森路,冯建宇,张玲,古丽娜·巴德尔汗,祖力卡提阿衣·阿布都拉,王新旗..高负担地区肺结核密切接触者中结核分枝杆菌潜伏感染者预防性治疗接受意愿及影响因素研究[J].中国防痨杂志,2024,46(2):165-172,8.基金项目
新疆维吾尔自治区卫生健康委青年医学科技人才专项科研项目(WJWY-202239) （WJWY-202239）
新疆维吾尔自治区科学技术协会青年人才托举工程项目(RCTJ42) （RCTJ42）
新疆维吾尔自治区自然科学基金项目(2023D01C57)Young Medical Science and Technology Talents Special Scientific Research Project of Health Commission of Xinjiang Uygur Autonomous Region(WJWY-202239) （2023D01C57）
Science and Technology Association Young Talent Lifting Project of Xinjiang Uygur Autonomous Region(RCTJ42) （RCTJ42）
Xinjiang Uygur Autonomous Region Natural Science Foundation Project(2023D01C57) （2023D01C57）
