中国感染控制杂志2024，Vol.23Issue(1)：42-48,7.DOI:10.12138/j.issn.1671-9638.20243007
鲍曼不动杆菌无菌体液感染患者归因危险度多中心回顾性队列研究
A multicenter retrospective cohort study on the attributable risk of patients with Acinetobacter baumannii sterile body fluid infection
摘要
Abstract
Objective To investigate the attributable risk(AR)of Acinetobacter baumannii(AB)infection in criti-cally ill patients.Methods A multicenter retrospective cohort study was conducted among adult patients in inten-sive care unit(ICU).Patients with AB isolated from sterile body fluid and confirmed with AB infection in each cen-ter were selected as the infected group.According to the matching criteria that patients should be from the same pe-riod,in the same ICU,as well as with similar APACHE Ⅱ score(±5 points)and primary diagnosis,patients who did not infect with AB were selected as the non-infected group in a 1:2 ratio.The AR was calculated.Results The in-hospital mortality of patients with AB infection in sterile body fluid was 33.3％,and that of non-infected group was 23.1％,with no statistically significant difference between the two groups(P=0.069).The AR was 10.2％(95％CI:-2.3％-22.8％).There is no statistically significant difference in mortality between non-infected pa-tients and infected patients from whose blood,cerebrospinal fluid and other specimen sources AB were isolated(P＞0.05).After infected with AB,critically ill patients with the major diagnosis of pulmonary infection had the high-est AR.There was no statistically significant difference in mortality between patients in the infected and non-infec-ted groups(P＞0.05),or between other diagnostic classifications.Conclusion The prognosis of AB infection in critically ill patients is highly overestimated,but active healthcare-associated infection control for AB in the ICU should still be carried out.关键词
鲍曼不动杆菌/归因危险度/预后/无菌体液/血/多中心队列研究Key words
Acinetobacter baumannii/attributable risk/prognosis/sterile body fluid/blood/multicenter cohort study分类
预防医学引用本文复制引用
何磊,夏琴,何莉,刘晞照,舒昌惠,李荣琴,陶红英,陈泽芬,姜道彬,刘丁,郑小芳,邱荷语,吴淑梅,吴晓英,崔金兰,谢首佳..鲍曼不动杆菌无菌体液感染患者归因危险度多中心回顾性队列研究[J].中国感染控制杂志,2024,23(1):42-48,7.基金项目
重庆市卫生计生委重点项目(20141024) （20141024）
