探讨健康体检中超声弹性成像应变比值鉴别甲状腺结节良恶性的价值OACSTPCD

Objective:To explore the value of ultrasound elastography strain ratio(SR)and conventional ultrasound in dif-ferentiating benign and malignant thyroid nodules(ACR TI-RADS 4 and above)in healthy physical examination.Methods:A retrospective analysis was conducted on patients with thyroid nodules(ACR TI-RADS 4 and above)who underwent health ex-aminations at the hospital from January 1,2020 to December 31,2022.A total of 79 thyroid nodules confirmed by postopera-tive or pathology underwent conventional ultrasound(with a proposed ACR TI-RADS score of 5 or above considering malignan-cy)and ultrasound elastography SR examination,with a threshold of 2.73.The pathological results were used as the gold stan-dard to construct the receiver operating characteristic(ROC)curve,to analyze the area under the curve(AUC),and evaluate the value of the two methods in the differential diagnosis of benign and malignant thyroid nodules in physical examination.Re-sults:Seventy-nine nodules(52 malignant and 27 benign)were confirmed by pathology.The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of ultrasound elastography SR and conventional ultrasound in differen-tial diagnosis of benign and malignant thyroid nodules(ACR TI-RADS 4 and above)were 92.31%,88.89%,91.14%,94.12%,85.71%;67.30%,62.96%,65.82%,77.78%,50.0%.The AUC of the ultrasound elastography SR group and the conventional ultrasound group were 0.906 and 0.651,respectively,and the difference was statistically significant(P<0.05).Conclusion:The SR of ultrasound elastography in physical examination is more accurate in the differential diagnosis of benign and malignant nodules in ACR TI-RADS 4 and above thyroid nodules than that in the conventional ultrasound group.