中国食品学报2023，Vol.23Issue(12)：219-228,10.DOI:10.16429/j.1009-7848.2023.12.023
膳食中双酚类化合物的污染水平和风险评估
Bisphenols in Diets:Contaminated Levels and Risk Assessment
摘要
Abstract
Bisphenols(BPs)are suspected posing potential endocrine disrupting properties.Occurrence of BPs has been reported in environmental matrices.BPs might migrate into foodstuffs through food packaging materials or contaminated water and soil.Information on the occurrence of bisphenols,other than BPA,in foodstuffs,however,is scarce.Dietary exposure is of paramount importance way for human health.In this study,eight BPs,including BPA,BPS,BPP,BPB,BPAP,BPAF,BPF and BPZ,were analyzed in market foodstuffs(N=278)collected from Guangyuan,Sichuan,China,using ultra-performance liquid chromatography tandem mass spectrometry(UPLC-MS/MS)foodstuffs were divided into ten categories of beverages,dairy products,eggs,cquatic foods,cereals,meats,fruits,vegetables,canned food and pack-aged drinking water.Bisphenols were found in the majority(76.3％)of the food samples,and the total concentrations of bisphenols(∑BPs:sum of eight bisphenols)were in the range of below the limit of detection(LOD)to 59.08 μg/kg,with an overall mean value of 3.12 μg/kg.The higher overall mean concentration of ∑BPs was found in canned food,cereals,cquatic foods and vegetables.The predominant bisphenol analogues found in foodstuffs were BPA and BPS,which accounted for 77.9％and 14.4％of the total BPs concentrations,respectively.On the basis of measured concentra-tions and daily ingestion rates of foods,the daily dietary intakes of bisphenols(calculated from the mean concentration)were estimated to rang from 42.59 ng/kg bw/d to 96.54 ng/kg bw/d for different age and gender groups.BPA contributed to the majority of the total intakes of the BPs,followed by BPs.The daily dietary intakes of BPs showed a decrease with the growth of the age.It should be noted that dietary intakes of people aged 2-19 year old(critical time of devel-opment,87.96 ng/kg bw/d)were obviously higher than that of aged above 19(48.05 ng/kg bw/d).Based on the t-TDI set by EFSA(4 μg/kg bw/d for BPA),the BPs through dietary intake pose low risks on the general population even summa-rization exposure levels of different BPs.However,the production and application of BPA analogues are increasing world-wide,and the health risks caused by BPA analogues should be continuously concerned.关键词
UPLC-MS/MS/双酚类化合物/污染水平/膳食暴露评估Key words
UPLC-MS/MS/bisphenol compounds/contaminated levels/dietary exposure assessment引用本文复制引用
佐鹏,谭学蓉,刘少颖,杨容,李波,穆芳,石卜芳..膳食中双酚类化合物的污染水平和风险评估[J].中国食品学报,2023,23(12):219-228,10.基金项目
广元市科技计划项目(19ZDYF0016) （19ZDYF0016）
