儿童嗜酸性粒细胞性胃肠道疾病121例胃镜特点分析OACSTPCD

Objective To summarize the gastroscopic findings of pediatric eosinophilic gastrointestinal diseases(EGIDs)with upper gastrointestinal tract involvement.Methods Collect and analyze the results of gastroscopy in children with EGIDs with upper gastrointestinal tract involvement admitted to the Gastroenterology Department,Beijing Children's Hospital,Capital Medical University from January 1,2016 to December 31,2022.Results A total of 121 children with EGIDs were included in the study(89 males and 32 females).There were 31 cases(25.62％)of esophageal involvement,39 cases(32.23％)of gastric involvement,and 85 cases(70.25％)of duodenum involvement.Common abnormalities in patients with esophageal involvement were mucosal roughness(32.26％),hyperemia and edema(25.81％),rings(9.68％),erosion(9.68％),and erythema(9.68％),and gastroscopy was normal in 45.16％of patients.Gastric mucosal hyperemia and edema(100％),mottling(71.79％),erythema(25.64％),mucous lake turbidity or bile dyed(23.08％),hemorrhage(20.51％),erosion(15.38％),mucosal roughness(15.38％),and ulcers(12.82％)were observed in gastric involvement patients.Gastroscopy was normal in 28.24％of patients with duodenal involvement,the common abnormalities of whom were mucosal hyperemia and edema(58.82％),ulcer(31.76％),white exudates(23.53％),erythema(22.35％),roughness(22.35％),and erosion(15.29％),etc.The incidence of ulcers in children with duodenal involvement was higher than that in children with gastric involvement(x2=5.011,P＜0.05),while hemorrhage was more common in the stomach(x2=5.940,P＜0.05).Conclusion The gastroscopic manifestations of pediatric EGIDs are non-specific.Mucosal roughness,hyperemia and edema and rings are observed in patients with esophageal involvement.There is mucosal hyperemia and edema,mottling and erythema in patients with gastric involvement.In children with duodenal involvement,the common abnormalities are mucosal hyperemia and edema,ulcers,white exudates and erythema.About half of children with esophageal involvement and a quarter of children with duodenal involvement have normal gastroscopic findings.