Diet and physical activity influence the composition of gut microbiota,benefit on Alzheimer''''s diseaseOACSTPCD
Alzheimer''s disease is a neurodegenerative disease with complex etiology.Gut microbiota influences the gutbrain axis,which may affect pathways related to the pathogenesis of Alzheimer''s disease.Additionally,diet and physical activity are likely to affect the pathology of Alzheimer''s disease as well as the gut microbiota.This demonstrates that it may be possible to prevent or halt the progression of Alzheimer''s disease by regulating the gut microbiota using diet and physical activity strategies.Therefore,the present study reviews the association between these two interventions and gut microbiota in the human body.It also summarizes how these two interventions benefit Alzheimer''s disease.Furthermore,the primary limitations of these two interventions are discussed and promising strategies are proposed,which may be beneficial to further study and develop the intervening measure for the progression of Alzheimer''s disease.
Jinyue Zhou;Min Tang;Wanyi Li;Rui Fang;Chunlan Tang;Qinwen Wang;无;
School of Public Health,Health Science Center,Ningbo University,Ningbo 315211,ChinaDepartment of Neurology,Ningbo Rehabilitation Hospital,Ningbo 3151000,ChinaSchool of Public Health,Health Science Center,Ningbo University,Ningbo 315211,China Department of Neurology,Ningbo Rehabilitation Hospital,Ningbo 3151000,China Ningbo Institute of Life and Health Industry,University of Chinese Academy of Sciences,Ningbo 315100,ChinaKey Laboratory of Diagnosis and Treatment of Digestive System Tumors of Zhejiang Province,Ningbo 315100,China
轻工业
Alzheimer’s diseaseGut microbiotaBrain-gut axisDietPhysical activity
《Food Science and Human Wellness》 2024 (002)
P.541-555 / 15
financially supported by National Natural Science Foundation of China(32171035);the major fund project of Ningbo Science and Technology Bureau(2019B10034);Opened-end Fund of Key Laboratory(KFJJ-202101,ZPKLP202202);Public Project of Ningbo(202002N3167);Project of Yinzhou(2022AS025);Ningbo Rehabilitation Hospital(2022KY02);sponsored by a K.C.Wong Magna Fund in Ningbo University。
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