环境与职业医学2024，Vol.41Issue(1)：25-33,9.DOI:10.11836/JEOM23202
大气PM2.5与O3对宁夏地区人群循环系统疾病死亡的影响及其交互作用
Individual and interactive effects of atmospheric PM2.5 and O3 on mortality of circulatory system diseases in Ningxia
摘要
Abstract
[Background]The impact of atmospheric fine particulate matter(PM2.5)and ozone(O3)on the mortality of circulatory system diseases cannot be ignored.However,whether the interaction between PM2.5 and O3 can affect population health is rarely reported and requires study. [Objective]To investigate the individual and interactive impacts of atmospheric PM2.5 and O3 on the mortality of circulatory system diseases in the population of Ningxia region. [Methods]The data of 119647 deaths due to circulatory system diseases,daily average concen-trations of atmospheric pollutants,and meteorological data in Ningxia from 2013 to 2020 were retrieved.PM2.5 was divided into low,medium,and high concentrations according to the primary and secondary national limits(35 and 75 μg·m-3)of the Ambient air quality standards.Similarly,O3 was divided into low,medium,and high concentrations according to the national limits(100 and 160 μg·m-3).Using a generalized additive mixed model based on quasi Poisson distribution,the impacts of atmospheric PM2.5 and O3 as well as their interaction on the mortality of circulatory system diseases were analyzed using the population data of Ningxia region. [Results]During the target period,males and the≥65 year group accounted for larger proportions of deaths due to circulatory system diseases(55.47%and 79.87%respectively).The daily average concentration of PM2.5(40.25 μg·m-3)exceeded the national primary limit.In the single pollution model,the highest cumulative lag effects for mortality from circulatory system diseases were PM2.5 exposure over previous 1 d(lag01)and O3 exposure for previous 2 d(lag02),and their excess risk(ER)values were 1.03%(95%CI:0.67%,1.40%)and 1.02%(95%CI:0.57%,1.50%),respectively.The results of concentration stratification analysis showed that the most significant risks of death from circulatory system diseases[ER(95%CI):1.12%(0.32%,1.92%)and 0.95%(0.13%,1.79%)respectively]were found at medium PM2.5 and O3 concentrations.The interaction analysis revealed that under,a synergistic effect on the risk of death from circulatory system diseases was identified(relative excess risk due to interaction=3.08%,attributable proportion of interaction=2.90%,synergy index=1.89)when considering the coexistence of PM2.5 and O3 above the primary limit.As the concentrations of PM2.5 and O3 increased,the synergistic effect increased the risk of death from circulatory system diseases in the general population,men,women,and the≥65 years group. [Conclusion]Both atmospheric PM2.5 and O3 can increase the risk of death from circulatory system diseases,and the two pollutants have a synergistic effect on the risk of death from circulatory system diseases.关键词
大气污染/PM2.5/O3/死亡风险/交互作用Key words
air pollutant/fine particulate matter/ozone/risk of death/interactive effect分类
医药卫生引用本文复制引用
王栋帅,董学昊,王金霞,石运昊,张翰卿,周思杰,张亚娟..大气PM2.5与O3对宁夏地区人群循环系统疾病死亡的影响及其交互作用[J].环境与职业医学,2024,41(1):25-33,9.基金项目
宁夏自然科学基金项目(2022AAC03142) This study was funded. （2022AAC03142）
