首页|期刊导航|The Journal of Biomedical Research|Causal genetic regulation of DNA replication on immune microenvironment in colorectal tumorigenesis: Evidenced by an integrated approach of trans-omics and GWAS

Causal genetic regulation of DNA replication on immune microenvironment in colorectal tumorigenesis: Evidenced by an integrated approach of trans-omics and GWAS

Sumeng Wang Silu Chen Huiqin Li Shuai Ben Tingyu Zhao Rui Zheng Meilin Wang Dongying Gu Lingxiang Liu

The Journal of Biomedical Research2024，Vol.38Issue(1)：P.37-50,14.

The Journal of Biomedical Research2024，Vol.38Issue(1)：P.37-50,14.DOI:10.7555/JBR.37.20230081

Causal genetic regulation of DNA replication on immune microenvironment in colorectal tumorigenesis: Evidenced by an integrated approach of trans-omics and GWAS

Sumeng Wang ¹Silu Chen ²Huiqin Li ³Shuai Ben ²Tingyu Zhao ¹Rui Zheng ²Meilin Wang ²Dongying Gu ⁴Lingxiang Liu¹

作者信息

1. Department of Oncology,the First Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210029,China
2. Department of Environmental Genomics,Jiangsu Key Laboratory of Cancer Biomarkers,Prevention and Treatment,Collaborative Innovation Center for Cancer Personalized Medicine,Nanjing Medical University,Nanjing,Jiangsu 211166,China Department of Genetic Toxicology,the Key Laboratory of Modern Toxicology of Ministry of Education,Center for Global Health,School of Public Health,Nanjing Medical University,Nanjing,Jiangsu 211166,China
3. Department of Biostatistics,Center for Global Health,School of Public Health,Nanjing Medical University,Nanjing,Jiangsu 211166,China
4. Department of Oncology,Nanjing First Hospital,Nanjing Medical University,Nanjing,Jiangsu 210006,China.
折叠

摘要

关键词

trans-omics/DNA replication/tumor immune microenvironment/causal mediation/colorectal tumorigenesis

分类

医药卫生

引用本文复制引用

Sumeng Wang,Silu Chen,Huiqin Li,Shuai Ben,Tingyu Zhao,Rui Zheng,Meilin Wang,Dongying Gu,Lingxiang Liu..Causal genetic regulation of DNA replication on immune microenvironment in colorectal tumorigenesis: Evidenced by an integrated approach of trans-omics and GWAS[J].The Journal of Biomedical Research,2024,38(1):P.37-50,14.

基金项目

supported by the National Natural Science Foundation of China(Grant No.82173601) （Grant No.82173601）

Yili&Jiangsu Joint Institute of Health(Grant No.yl2021ms02). （Grant No.yl2021ms02）

The Journal of Biomedical Research

ISSN：1674-8301

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