中国食品添加剂2024，Vol.35Issue(2)：48-57,10.DOI:10.19804/j.issn1006-2513.2024.2.007
柚皮苷制备柚皮苷二氢查尔酮的氢化工艺优化
Optimization of hydrogenation process for preparation of naringin dihydrochalcone from naringin
摘要
Abstract
In order to investigate the preparation and synthesis process of naringin dihydrochalcone,the hydrogenation process in the preparation process was optimized by single factor test and response surface test,and the hydrogenated products were purified and identified.The optimum hydrogenation process was as follows:at 25℃and a pressure of 0.5 MPa,the addition of naringin was 5.8 g/L,the amount of NaOH was 0.21％,the reaction solvent was water,the reaction time was 7.90 h,the catalyst was 10％palladium carbon(Pd/C),and the catalyst amount was 0.16％.Under these conditions,the synthesis yield of naringin dihydrochalcone was 93.11％.After crystallization,the synthesized product was identified by HPLC and nuclear magnetic resonance techniques,and the product was determined to be naringin dihydrochalcone,and the purity was 92％.The process had the advantages of low reaction temperature,small reaction pressure,short reaction time,high yield of naringin dihydrochalcone,and easy purification and preparation of the product.The study provides reference for an efficient hydrogenation and refining process for industrial production of naringin dihydrochalcone.关键词
柚皮苷/柚皮苷二氢查尔酮/氢化/钯碳/响应面Key words
naringin/naringin dihydrochalcone/hydrogenation/palladium carbon(Pd/C)/response surface分类
轻工纺织引用本文复制引用
黄凯,毛子剑,刘学魁,倪辉,李利君,李清彪..柚皮苷制备柚皮苷二氢查尔酮的氢化工艺优化[J].中国食品添加剂,2024,35(2):48-57,10.基金项目
国家自然科学基金(U1805235). （U1805235）
