关于完善科研机构实验动物福利伦理管理的对策建议OA

Life science research is inseparable from animal experiments,and how to strengthen the supervision and management of experimental animal welfare and ethics is concerned and focused on by relevant personnel and authorities.Regulations on the Management of Laboratory Animals was published in 1988,whereafter,several relevant regulations and standards successively published,nearly 100 institutions certified by Association for Assessment and Accreditation of Laboratory Animal Care(AAALAC),and laboratory animal institution accreditation system established by China National Accreditation Service for Conformity Assessment(CNAS),which strongly safeguarded the experimental animals with high quality,also laid a solid foundation for bioscientific research in China.In general,the construction of animal welfare system in China was still relatively behind other countries,especially such problems as heavy workload of review of animal ethics,poor ethical awareness of relevant personnel,lack of supervision during animal experiment operation,insufficient supervision by authorities and gaps in the punishment mechanism for animal ethics issues.Relevant authorities were recommended to strictly develop ethical requirements for declaration of scientific research projects,improve the supervision,training and publicity of animal welfare and ethnics during experimental process,explore to implement"peer review"system and to develop an punishment system for ethical issues.In the paper,the status of domestic animal welfare management was summarized,and existing problems were analyzed to propose relevant countermeasures,with a view to providing a reference for management of experimental animal welfare and ethics in scientific institutions in China.