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茶天然产物缓解痤疮的作用机制研究进展OA北大核心CSTPCD

Research Progress on the Mechanism of Natural Tea Components in Alleviating Acne

中文摘要英文摘要

茶因其明确的保健功能与健康益处备受人们青睐.随着对茶活性成分的深入研究,茶天然产物已被证实能够对多种疾病模型具有改善效果.痤疮是一种流行性高、复发率高的炎性皮肤病,除传统临床诊疗外,以敷贴、皮肤护理、膳食改善为代表的补充替代治疗也受到欢迎.目前市场上,越来越多的祛痘功效宣称产品在原料中添加茶源活性成分,以茶多酚、咖啡碱、茶氨酸、茶皂素为代表的茶叶天然产物在缓解痤疮上表现出极大的潜力.综述了茶叶不同功效成分在抑制皮脂分泌、减轻粉刺发生、改善皮肤微生物失调、减缓皮肤局灶性炎症的作用及分子机制,以期为含茶功效宣称产品的研发提供参考.

Tea,as a natural beverage,is highly favored due to its clear health benefits.With in-depth research on the active ingredients of tea in recent years,it has been confirmed that natural components can have positive effects on various disease models.Acne is an inflammatory skin disease with a high prevalence and recurrence rate.In addition to traditional clinical diagnosis and treatment,complementary and alternative therapies represented by patches,skin care,and dietary improvement are also popular.In the market,more and more acne control products claim to add tea active ingredients to the raw materials.Natural components such as tea polyphenols,caffeine,theanine and tea saponins have shown great potential in alleviating acne.In this paper,the effects and molecular mechanisms of different functional components of tea on inhibiting sebum secretion,alleviating acne,improving skin microbial imbalance,and alleviating skin focal inflammation were reviewed,in order to provide reference for the research and development of tea natural products.

吴致远;王凯博;陈思霖;赵碧;申时全

云南省农业科学院茶叶研究所/云南省茶学重点实验室,云南 昆明 650205

农业科学

天然产物缓解痤疮

teanatural productsmitigationacne

《茶叶科学》 2024 (001)

16-26 / 11

云南省重大科技专项计划(202102AE090038)、云南省基础研究计划项目(202301AU070129)、云南省茶学重点实验室开放基金(2023YNCX010、2022YNCX004)、云南省农业科学院应用基础预研专项(2023KYZX-03)

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