黄连厚朴复方水提物对鸡柔嫩艾美耳球虫病的疗效试验OACSTPCD

In the study,the compound Chinese herbal medicine was combined with Coptis chinensis and Magnolia officinalis as the core to explore its anti-coccidiosis effect,in order to enhance the efficacy of the drug and improve the growth performance of sick chickens.The ex-perimental results showed that the compound water extract of Coptis chinensis and Magnolia officinalis achieved a remarkable anticoccidial effect,as indicated by an anticoccidial index(ACI)of 169.48.This herbal compound effectively mitigated the pathological damage inflicted by Eimeria tenella on the cecum in the chicks,reduced their oocyst discharge,diminished the occurrence of bloody stools in them,and re-stored their growth performance.The analysis of the cytokine levels in the peripheral serum revealed that this herbal compound was able to re-duce the concentrations of pro-inflammatory factors and raised the levels of IL-10.Moreover,the compound water extract of Coptis chinensis and Magnolia officinalis had antioxidant properties during infection,elevating the levels of antioxidant enzymes and lowering MDA and NO in the chicks.In conclusion,the compound water extract of Coptis chinensis and Magnolia officinalis indicated a promising potential as a natural Chinese herbal medicine for the treatment of E.tenella infection,providing an effective alternative to chemical synthetic drugs such as antibi-otics.