分析化学2024,Vol.52Issue(2):145-156,12.DOI:10.19756/j.issn.0253-3820.231076
基于智能手机的可视化生物传感器在即时检测中的研究进展
Research Advance on Smartphone-based Visual Biosensor in Point-of-Care Testing
摘要
Abstract
Human physiological indicators have become an important standard for assessing health in modern society.Traditional detection methods often require a separate laboratory,complex operation process and long detection time,so it is urgent to develop portable,fast and accurate on-site detection technologies for bioanalysis.Point-of-care testing(POCT),which differs from traditional laboratory testing,can realize the rapid in situ detection of biomarkers without the complicated analytical process of the laboratory.Smartphones,which are an essential tool in our daily life,not only have independent operating systems and built-in storage functions,but also have high-definition cameras,which have great application potential in POCT visualization.The combination of various biosensing technologies and smartphones has developed into a new direction in the field of POCT.This review mainly introduced the research progress of smartphone-based visual biosensors in POCT in recent years,including colorimetric sensors,fluorescence sensors,chemiluminescence sensors and electrochemiluminescence sensors.Finally,the problems faced by smart-phone-based visual biosensors in the application of POCT were summarized,and their future development was prospected.关键词
智能手机/可视化生物传感器/即时检测/评述Key words
Smartphone/Visual biosensor/Point-of-care testing/Review引用本文复制引用
向宪昕,孙华悦,柴会宁,喻琨,曲丽君,张光耀,张学记..基于智能手机的可视化生物传感器在即时检测中的研究进展[J].分析化学,2024,52(2):145-156,12.基金项目
国家自然科学基金项目(Nos.22204089,21801158)、山东省自然科学基金项目(No.ZR2020QB092)和省部共建生物多糖纤维成形与生态纺织国家重点实验室(青岛大学)基金项目(Nos.ZKT23,KF2020201,GZRC202025)资助.Supported by the National Natural Science Foundation of China(Nos.22204089,21801158),the Natural Science Foundation of Shandong Province,China(No.ZR2020QB092)and the Opening Fund of State Key Laboratory of Bio-Fibers and Eco-Textiles(Qingdao University)(Nos.ZKT23,KF2020201,GZRC202025). (Nos.22204089,21801158)